DGAT
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB20254 | Teglicar | 250694-07-6 | Teglicar (ST-1326) is a potent, selective and reversible inhibitor of liver carnitine palmitoyl-transferase 1 (L-CPT1) with IC50 of 0.68 uM, Ki of 0.36 uM. |
| FB06129 | T863 | 701232-20-4 | T863 is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells. |
| FB09112 | PF-04620110 | 1109276-89-2 | PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM. |
| FB01573 | LCQ-908 | 956136-95-1 | LCQ-908 is a potent and oral active diacylglycerol acyltransferase 1 (DGAT1) inhibitor, used as anti-obesity and anti-diabetic agents. |
| FB10754 | Etomoxir | 124083-20-1 | Etomoxir is a cell-permeable, irreversible, and stereospecific inhibitor of carnitine palmitoyltransferase (CPT)-1 and DGAT activity in the mitochondria of rat heart H9c2 myoblastic cells at a concentration of 1-80 μM and 40 μM, respectively. |
| FB01455 | DGAT1-IN-1 | 1449779-49-0 | DGAT1-IN-1 is a potent DGAT1 inhibitor with IC50 of < 10 nM (cell lysate from Hep3B cells overexpressing human DGAT1). |
| FB11011 | DGAT1 Inhibitor C9 | 1137671-16-9 | DGAT1 inhibitor C9 is an orally bioavailable benzimidazole diacylglycerol acyltransferase 1 (DGAT1) inhibitor. |
| FB03406 | DGAT1 Inhibitor 2 | 942999-61-3 | DGAT-1 inhibitor 2 is an effective inhibitor of DGAT-1 and an antiobesity agent. |
| FB02302 | AZD7687 | 1166827-44-6 | AZD7687 is a potent and selective DGAT1 inhibitor with an IC50 of 80 nM for hDGAT1. |
| FB07677 | ABT-046 | 1031336-60-3 | ABT-046 is a potent, selective, and orally bioavailable Diacylglycerol acyltransferase 1 (DGAT-1 ) inhibitor (IC50= 8 nM). |
| FB06130 | A 922500 | 959122-11-3 | A 922500 is a potent, selective, and orally bioavailable DGAT-1 inhibitor with IC50 values of 7 nM and 24 nM for human and mouse DGAT-1 respectively. |