PAFR
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB12113 | YM-264 | 131888-54-5 | YM-264 is a selective, potent and orally active platelet-activating factor (PAF) antagonist with a pKi value of 8.85 for rabbit platelet membranes. |
| FB04723 | Yangambin | 13060-14-5 | Yangambin, a natural product isolated and purified from the leaves of Ocotea duckei Vattimo., is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF) and therefore constitutes a potential therapeutic agent in different shock states where abnormal PAF release is supposed to play an important role. |
| FB16869 | SDZ 62-434 | 115621-95-9 | SDZ 62-434 is a PAF antagonist which showed strong antiproliferative activity (2-40μM)after 24, 48, and 72h of incubation in CCL-121, CCL-218 and HTB-38 cell lines. |
| FB04711 | Piperenone | 57625-31-7 | Piperenone, a PAF-acether antagonist isolated and purified from the stems of Piper schmidtii Hook f., has anti-platelet-activating factor(PAF) activity. |
| FB02447 | PAF (C16) | 74389-68-7 | PAF (C16) is an endogenous platelet-activating factor (PAF) and ligand for PAF receptors. |
| FB04688 | Niranthin | 50656-77-4 | Niranthin, a natural product isolated and purified from the herbs of Phyllanthus amarus, exhibits anti-hepatitis B virus activity both in vitro and in vivo, and antiinflammatory and antiallodynic actions which are probably mediated through its direct antagonistic action on the PAF receptor binding sites. |
| FB01880 | Ginkgolide B | 15291-77-7 | Ginkgolide B, an important active terpenoid from Ginkgo biloba leaves, a PAFR antagonist with IC50 of 3.6 μM, is reported to increase cell viability and decrease cell apoptosis. |
| FB05205 | Futoenone | 19913-01-0 | Futoenone, a natural product isolated and purified from the stem of Piper kadsura., inhibitory activities against matrix metalloproteinases, the molecular modelings of these compounds indicate the preferred binding of the P2′ site of the enzymes., and exhibits both platelet activating factor receptor(PAF)and 5-lipoxygenase antagonist activity. |
| FB01688 | Etizolam | 40054-69-1 | Etizolam is a benzodiazepine analog with antagonistic activity on platelet-activating factor (PAF) and other signal-transducing molecules with amnesic, anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. |
| FB11993 | E-6123 | 131614-02-3 | E-6123 is a platelet-activating factor (PAF) receptor antagonist. |