Diterpenoids
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB11000 | α-Cembrenediol | 57605-80-8 | VEGFR inhibitor TC1 acts in angiogenesis inhibitory in multiple breast cancer cell lines by significantly reducing the activated VEGFR2 levels. |
| FB08496 | Triptonide | 38647-11-9 | Triptonide, a natural product isolated and purified from the herb of Tripterygium wilfordii Hook.f. with antileukemic, antitumor, anti-inflammatory activities, is effective in the treatment of autoimmune diseases. |
| FB08385 | Triptolide | 38748-32-2 | Triptolide, a diterpene triepoxide extracted from the Chinese herb Tripterygium wilfordii, functions as a NF-κB inhibitor with dual actions by disruption of p65/CBP interaction and by reduction of p65 protein. |
| FB06604 | Trigothysoid N | 1501943-08-3 | Trigothysoid N is a natural product isolated and purified from the twigs and leaves of Trigonostemon thyrsoideum. |
| FB09657 | Tanshinone IIB | 17397-93-2 | Tanshinone IIB (TSB), a natural product isolated and purified from the roots of Salvia miltiorrhiza, can significantly inhibit the DNA laddering, cytotoxicity and apoptosis of rat cortical neurons induced by staurosporine in a concentration-dependent manner. Tanshinone IIB showed inhibitory effect on PL(pro) with IC50 value of 10.7μM and less inhibitory effect on 3CLpro with IC50 value of 24.8μM. |
| FB07650 | Steviol | 471-80-7 | Steviol is the aglycon derivative of steviol glycosides, which are natural sweeteners isolated from S. rebaudiana. Steviol inhibits human organic anion transporters (hOATs) in uptake assays using murine cells from the S2 segment of proximal tubules. Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity. |
| FB16797 | Rosmariquinone | 27210-57-7 | Rosmariquinone showed inhibitory effect on PL(pro) and 3CLpro with IC50 values of 30μM and 21.1μM, respectively. |
| FB08829 | Rebaudioside A | 58543-16-1 | Rebaudioside A, an α-glucosidase inhibitor with IC50 of 35.01 μg/mL. is a steviol glycoside isolated and purified from the leaves of Stevia rebaudiana Bertoni.. |
| FB08373 | Pimaric Acid | 127-27-5 | Pimaric acid is a natural product isolated and purified from the herbs of Aralia cordata having a potent anti-atherosclerotic activity with inhibitory action on matrix metalloproteinase-9 production and cell migration in TNF-α-induced human aortic smooth muscle cells. |
| FB08373 | Pimaric Acid | 127-27-5 | Pimaric acid is a natural product isolated and purified from the herbs of Aralia cordata having a potent anti-atherosclerotic activity with inhibitory action on matrix metalloproteinase-9 production and cell migration in TNF-α-induced human aortic smooth muscle cells. |
| FB11131 | Ovatodiolide | 3484-37-5 | Ovatodiolide is a macrocyclic diterpenoid isolated from Anisomeles indica, showing therapeutic potential for the treatment of allergic asthma. |
| FB09417 | Oridonin | 28957-04-2 | Oridonin is an antitumor agent, a diterpenoid purified from Rabdosia rubescens. |
| FB06581 | Neoprzewaquinone A | 630057-39-5 | Neoprzewaquinone A, a natural product isolated and purified from the roots of Salvia miltiorrhiza, has algicidal effect on M. |
| FB04560 | Nagilactone C | 24338-53-2 | Nagilactone C, a natural product isolated and purified from the herbs of Podocarpus neriifolius, possesses potent antiproliferative activity against human fibrosarcoma and murine colon carcinoma tumor cell lines exhibiting ED50 values of 2.3 and 1.2 mg/mL, respectively. |
| FB04560 | Nagilactone C | 24338-53-2 | Nagilactone C, a natural product isolated and purified from the herbs of Podocarpus neriifolius, possesses potent antiproliferative activity against human fibrosarcoma and murine colon carcinoma tumor cell lines exhibiting ED50 values of 2.3 and 1.2 mg/mL, respectively. |
| FB09926 | Lathyrol | 34420-19-4 | Lathyrol is a natural product. |
| FB01621 | Kirenol | 52659-56-0 | Kirenol is a naturall occuring diterpenoid found in S. orientalis, which possess anti-oxidant, anti-inflammatory, anti-allergic, anti-adipogenic, and anti-arthritic activities. |
| FB01648 | Isopimaric Acid | 5835-26-7 | Isopimaric acid, a natural product isolated and purifed from the herbs of Daemonorops draco Blume, potently opens large conductance Ca-activated K+ channels and also possibly has an antagonistic interaction with reserpine which may render the antibiotics inactive. |
| FB09993 | Ingenol-3,4,5,20-Diacetonide | 77573-44-5 | Ingenol-3,4,5,20-diacetonide is a natural compound. |
| FB00063 | Honokiol | 35354-74-6 | Honokiol inhibits Akt activation and enhances ERK1/ERK2 phosphorylation, is a hydroxylated biphenyl compound isolated from the Chinese herb Magnolia officinalis with anticancer activities in a variety of cancer cell lines. |
| FB10814 | Heliosterpenoid B | N/A | Heliosterpenoid B is a natural product isolated and purfied from the whole plants of Euphorbia helioscopia, being potent inhibitors of P-glycoprotein (ABCB1). |
| FB10813 | Heliosterpenoid A | 2109805-68-5 | Heliosterpenoid A is a natural product isolated and purfied from the whole plants of Euphorbia helioscopia, being potent inhibitors of P-glycoprotein (ABCB1) and exhibiting cytotoxicity against MDA-MB-231 cell lines. |
| FB04097 | Ginkgolide C | 15291-76-6 | Ginkgolide C can enhance the cardiac function of rats in the body, is a flavone isolated from Ginkgo biloba leaves. |
| FB05102 | Galanolactone | 115753-79-2 | Galanolactone, a natural product isolated and purified from the rhizomes of Zingiber officinale Roscoe with cytotoxic activity, has anti-5-HT effect, a diterpenoid isolated from ginger, is related to antagonism of 5-HT3 receptors, exerts anti-obesity effect through down regulation of adipogenic transcription factors and adipogenic marker genes, and inhibits nitric oxide production with IC(50) values ranging from 5.5 to 28.5 μM. |
| FB06569 | Fischeria A | 221456-63-9 | Fischeria A is a natural product isolated and purified from the herbs of Euphorbia fischeriana. |
| FB16642 | Estragole | 140-67-0 | Estragole (4-Allylanisole), a relatively nontoxic volatile terpenoid ether, is a major component of the essential oil of many plants. Estragole dose-dependently blocks nerve excitability. Estragole displays anti-toxoplasma activity. |
| FB05097 | Eriocalyxin B | 84745-95-9 | Eriocalyxin B, a natural product isolated and purified from the herbs of Isodon eriocalyx, is a potent NF-kappaB inhibitor, can inhibit the NF-kappaB transcriptional activity but not that of cAMP response element-binding protein. |
| FB02942 | Diosbulbin B | 20086-06-0 | Diosbulbin B, a natural product isolated and purified from the roots of Dioscorea bulbifera, has potential anti-tumor effects which may be related to influencing the immune system for the first time. |
| FB03859 | Dihydrotanshinone I | 87205-99-0 | Dihydrotanshinone I, a natural product isolated and purified from the roots of Salvia miltiorrhiza Bge., exhibits dose-dependent inhibition towards HLM-catalyzed propofol glucuronidation. Dihydrotanshinone I showed inhibitory effect on PL(pro) with IC50 value of 4.9μM and less inhibitory effect on 3CLpro with IC50 value of 14.4μM. |
| FB00119 | Deacetyltaxol | 78432-77-6 | Deacetyltaxol is a natural product isolated and purified from the barks of Taxus chinensis (Pilger) Rehd. with cytotoxicity in human glial and neuroblastoma cell-lines. |
| FB01497 | Crocin II | 55750-84-0 | Crocin, a natural product with anti-inflammatory, antihyperlipidemic, antidepressant and anti-apoptotic effects, can ameliorate CCl4-induced liver injury via inhibition of inflammatory cytokines, caspase3 and oxidative stress along with modulation of liver metabolizing enzymes favoring elimination of CCl4 toxic metabolite, it's isolated and purified from the stigma of Crocus sativus L.. |
| FB08886 | Crocin | 42553-65-1 | Crocin, a natural product isolated and purified from the stigma of Crocus sativus L., can relax smooth muscles with a great potential to be a candidate for the treatment of asthma, protect liver and skeletal muscle tissue against exercise-induced oxidative damage by preventing reactive oxygen species (ROS) production, improve toxic effects of DZN via reducing lipid peroxidation and restoring altered contractile and relaxant responses in rat aorta, protect rat gastric mucosa against ethanol-induced injury via anti-inflammatory, anti-oxidative, anti-apoptotic and mucin-secretagogue mechanisms that are probably mediated by enhanced PGE2 release, significantly inhibit the growth of HO-8910 cells and arrest them in the G0/G1 phase, and also promote ovarian cancer HO-8910 cell apoptosis, most likely by increasing p53 and Fas/APO-1 expression, and then activating the apoptotic pathway regulated by Caspase-3. |
| FB00762 | Crocetin | 27876-94-4 | Crocetin, a saffron derivative, is an inhibitor of human lactate dehydrogenase 5 in the antiglycolytic approach against cancer. |
| FB04552 | Coronarin D | 119188-37-3 | Coronarin D, a natural product isolated and purified from the rhizomes of Hedychium coronarium, inhibits NF-κB activation pathway, which leads to inhibition of inflammation, invasion, and osteoclastogenesis, as well as potentiation of apoptosis. |
| FB05381 | Coronarin A | 119188-33-9 | Coronarin A, a natural product isolated and purified from the rhizomes of Hedychium coronarium with anti-inflammatory activity, exhibits good growth inhibition activities on HUVEC proliferation. |
| FB02956 | Carboxyatractyloside | 77228-71-8 | Carboxyatractyloside, a natural product isolated and purified from the roots of Atractylodes lancea (Thunb.) DC., induces the inhibitory effect of tamoxifen on nonspecific membrane permeability, and causes multiple organ dysfunction and can be fatal. |
| FB01204 | Cafestol | 469-83-0 | Cafestol is a bioactive substance isolated and extracted from coffee with potential medical uses. |
| FB06603 | Baccatin VIII | 1623410-10-5 | Baccatin VIII, a natural product isolated and purified from the twigs and leaves of Taxus yunnanensis, exhibits inhibitory effects on HL-60 and MCF-7, with IC50 values of 3.44 and 9.67 uM, respectively. |
| FB06605 | Baccatin IX | 1623410-12-7 | Baccatin IX is a natural product isolated and purified from the twigs and leaves of Taxus yunnanensis. |
| FB07585 | Baccatin III | 27548-93-2 | Baccatin III is a precursor to the anti-cancer drug paclitaxel, it's a natural product isolated and purified from the barks of Taxus chinensis. |
| FB09440 | Andrographolide | 5508-58-7 | Andrographolide is a naturally occuring NF-κB inhibitor. |
| FB03510 | 9-Hydroxy-13E-Labden-15-Oic Acid | 132915-47-0 | 9-Hydroxy-13E-labden-15-oic acid is a natural compound extracted from Leyssera gnaphaloidess. |
| FB01998 | 7beta-Hydroxylathyrol | 34208-98-5 | 7beta-Hydroxylathyrol is a natural product. |
| FB02855 | 7-Xylosyltaxol | 90332-66-4 | 7-Xylosyltaxol, a natural product isolated and purified from the barks of Taxus baccata, is a taxol (paclitaxel) derivative. |
| FB06186 | 20-Deoxyingenol | 54706-99-9 | 20-Deoxyingenol is a natural compound. |
| FB05383 | 15-Methoxypinusolidic Acid | 769928-72-5 | 15-Methoxypinusolidic acid, a natural product isolated and purified from the leaves of Biota orientalis, induces apoptosis in murine microglial cells, presumably via inhibition of the cell cycle progression, inhibits LPS-induced iNOS expression and NO production, independent on MAPK and NF-kappaB, suppresses adipocyte differentiation through the inhibition of PPARgamma-dependent adipogenic gene expression, and attenuates glutamate-induced excitotoxicity via stabilization of [Ca2+]i homeostasis and suppression of oxidative stress possibly through the actions on the NMDA receptors. |
| FB01652 | 14-Deoxyandrographolide | 4176-97-0 | 14-Deoxyandrographolide, a natural product isolated and purified from the herbs of Andrographis paniculata (Burm. |
| FB04385 | 14-Deoxy-11,12-Didehydroandrographolide | 42895-58-9 | 14-Deoxy-11,12-didehydroandrographolide, herbs of Andrographis paniculata (Burm. |
| FB04385 | 14-Deoxy-11,12-Didehydroandrographolide | 42895-58-9 | 14-Deoxy-11,12-didehydroandrographolide, herbs of Andrographis paniculata (Burm. |
| FB01039 | 10-Deacetylbaccatin III | 32981-86-5 | 10-Deacetylbaccatin-III is an intermediate for taxol analog preparations. |