IKK

IKK

货号 产品名 CAS号 信息
FB08686 WS3 1421227-52-2 WS3 is an Erb3 binding protein-1 (EBP1) and IκB kinase pathway modulator, it's a non-specific proliferative molecule and promotes β cell proliferation with EC50 of 28 nM.
FB05345 TPCA-1 507475-17-4 TPCA-1 is a selective and potent IKK-β inhibitor with IC50 value of 17.9 nM.
FB00079 SC514 354812-17-2 SC514 is a potent, reversible, ATP-competitive and highly selective IKK-β(IKK-2) inhibitor with IC50 value ranging in 3-12 µM.
FB16555 QUN97653 1893397-65-3 QUN97653 is a dual TBK1 and IKKε inhibitor, with IC50 values of 1 nM and 5.6 nM for TBK1 and IKKε, respectively.
FB04952 PS-1145 431898-65-6 PS-1145 is an IkappaB kinase (IKK) inhibitor with IC50 of 88 nM.
FB12610 PS 1145 2HCl 1049743-58-9 PS 1145 2HCl is a selective IκB kinase (IKK) inhibitor with IC50 of 100 nM.
FB12623 PR 39 (Porcine) 139637-11-9 PR 39 is an IκBα inhibitor, it's an antibacterial peptide, stimulates angiogenesis and inhibits inflammatory responses by selectively blocking proteasome degradation of IκBα.
FB02862 PHA-408 503555-55-3 PHA-408 is a potent, highly selective and ATP-competitive IKB kinase-2 (IKK-2) inhibitor (IC50: 40 nM).
FB12507 PF-184 1187460-81-6 PF-184 is a potent and selective IKKβ inhibitor with IC50 of 37 nM.
FB02331 MRT67307 1190378-57-4 MRT67307 is a dual inhibitor of the IKKe and TBK-1.
FB11558 MRT67307 2HCl 1781882-89-0 MRT67307 HCl is a potent and dual IKKε and TBK1 inhibitor.
FB10211 MRT67307 HCl 2095432-39-4 MRT67307 HCl is a potent and dual IKKε and TBK1 inhibitor with IC50 of 160 and 19 nM, respectively.
FB02106 MLN120B 783348-36-7 MLN120B is a potent and effective IKKbeta inhibitor.
FB07153 LY2409881 946518-61-2 LY2409881 is a selective inhibitor of IKK2 with IC50 of 30 nM and IC50 for IKK1 and other common kinases is at least one log higher.
FB00597 LY2409881 3HCl 946518-60-1 LY2409881 3HCl is a selective inhibitor of IKK2 with IC50 of 30 nM and IC50 for IKK1 and other common kinases is at least one log higher.
FB15379 INH14 200134-22-1 INH14 is an inhibitor of IKKα/IKKβ with IC50s of 8.97 and 3.59 μM respectively.
FB08984 IMD-0354 978-62-1 IMD-0354 is a synthetic selective NF-kB inhibitor and blocks IκBα phosphorylation in NF-κB pathway.
FB06658 IKKε-IN-1 1292310-49-6 IKKε-IN-1 is a potent IKKε inhibitor. It inhibits the in-situ ΙKΚ ε-mediated phosphorylation of IRF3 with an IC50 value of less than about 100 nM.
FB06858 IKK-3 Inhibitor 862812-98-4 IKK-3 inhibitor is a potent and selective inhibitor of IKK-epsilon kinase with IC50 of 40 nM and is inactive at IKK-α and IKK-β.
FB08479 IKK 16 873225-46-8 IKK 16 is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.
FB12349 IKK 16 HCl 1186195-62-9 IKK 16 HCl is a selective inhibitor of IκB kinase (IKK) with IC50s of 40, 70 and 200 nM for IKKβ, IKK complex and IKKα respectively.
FB15544 GSK8612 2361659-62-1 GSK8612 is a potent and highly selective Tank-binding Kinase-1 (TBK1) inhibitor with pIC50 of 6.8 for recombinant TBK1.
FB15544 GSK8612 2361659-62-1 GSK8612 is a potent and highly selective Tank-binding Kinase-1 (TBK1) inhibitor with pIC50 of 6.8 for recombinant TBK1.
FB17650 GS143   916232-21-8 GS143 is a selective IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. GS143 sup­presses NF-κB activation and transcription of target genes and does not inhibit proteasome activity. GS143 has anti-asthma effect .
FB02658 BX795 702675-74-9 BX795 is a potent and selective dual inhibitor of TBK1/PDK1 with IC50s of 2 nM/6 nM respectively, also inhibit Aurora B and IκB kinase ε (IKKε).
FB08739 BMS-345541 HCl 547757-23-3 BMS-345541 is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.
FB01341 BMS-345541 445430-58-0 BMS-345541 dose-dependently inhibits the TNF-α-stimulated phosphorylation of IκBα in THP-1 monocytic cells with an IC50 of ~4 μM.
FB07169 BI-605906 960293-88-3 BI-605906, an inhibitor of IKKβ, inhibits IKKβ with an IC50 value of 380 nM when assayed at 0.1 mM ATP.
FB01231 BAY 65-1942 R Form 758683-21-5 Bay 65-1942 is an ATP-competitive inhibitor that selectively targets IKKβ kinase.
FB06208 BAY 65-1942 600734-02-9 Bay 65-1942 is an ATP-competitive inhibitor that selectively targets IKKβ kinase.
FB04790 Bay 65-1942 HCl 600734-06-3 Bay 65-1942 HCl is an ATP-competitive inhibitor that selectively targets IKKβ kinase.
FB01505 BAY 11-7085 196309-76-9 BAY 11-7085 is an irreversible inhibitor of TNFα-induced IκBα phosphorylation with IC50 of 10 μM.
FB07842 BAY 11-7082 19542-67-7 BAY 11-7082 is a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation with IC50 of 10 μM in tumor cells. It also inhibits components of the ubiquitin system through inactivating the E2-conjugating enzymes Ubc (ubiquitin conjugating) 13 and UbcH7 and the E3 ligase LUBAC (linear ubiquitin assembly complex).
FB07026 Bardoxolone Methyl 218600-53-4 Bardoxolone methyl is an IKK inhibitor, showing potent proapoptotic and anti-inflammatory activities. It is also a potent Nrf2 activator and nuclear factor-κB (NF-κB) inhibitor.
FB00629 Bardoxolone 218600-44-3 Bardoxolone is a nuclear regulator factor (Nrf-2) activator.
FB03315 AZD3264 1609281-86-8 AZD3264 is an IkB-kinase IKK2 Inhibitor. IKK2 has been identified as one of the pathways to treat inflammatory conditions such as asthma, chronic pulmonary obstructive disorder (COPD) and rheumatoid arthritis.
FB02654 Amlexanox 68302-57-8 Amlexanox is a selective inhibitor of TBK1 and IKKε with IC50 values of ~1-2 μM.
FB09461 ACHP HCl 406209-26-5 ACHP HCl is a potent and selective IKK-2 inhibitor with IC50 of 8.5 nM.
FB15641 GSK8612 2361659-62-1
FB15641 GSK8612 2361659-62-1
<< 上一页 1 2 下一页 >>
felixbio版权所有2022，产品仅用于科研！
联系
我们