p53/MDM2 (stapled peptide) refers the stapled peptide target the interaction between p53 and MDM2.
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB17718 | peptide C19 | 2413879-97-5 | p53/MDM2 peptide C19 is a stapled peptide targeting p53/MDM2 interaction which could increase p53 activity. Its activity and toxicity is highly dependent on the match-up with a specific peptide sequence variant. |
| FB17725 | AcSAHp 538 | 932726-25-5 | AcSAHp 538 is a stabilized alpha-helix of p53 peptide that exhibits high affinity for hDM2. It reactivated the p53 tumor suppressor cascade by inducing the transcription of p53-responsive genes. Treatment with AcSAHp 538 led specific, dose-dependent cytotoxicity and apoptosis induction in SJSA-1 cells. |