NAMPT
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB03360 | STF-118804 | 894187-61-2 | STF-118804 is a highly specific and potent NAMPT inhibitor with IC50 values of 3-6 nM. |
| FB01537 | P7C3 | 301353-96-8 | P7C3 is a brain-penetrant NAMPT activator with proneurogenic and neuroprotective effect. |
| FB03977 | Nampt-IN-1 | 1698878-14-6 | Nampt-IN-1 is an inhibitor of NAMPT with IC50 of 18 nM (NCI-H1155 cell), 49 nM (Calu-6 cell), 333 nM (HCC1937 cell), and 389 nM (MCF-7 cell), respectively. |
| FB11237 | NAMPT Inhibitor C52 | 2109805-79-8 | NAMPT inhibitor C52 is a non-substrate isoindoline urea inhibitors of nicotinamide phosphoribosyltransferase (NAMPT) with nanomolar antiproliferative activity and preclinical pharmacokinetics properties which enabled potent antitumor activity when dosed orally in mouse xenograft models. |
| FB02800 | GNE-617 | 1362154-70-8 | GNE-617 is a potent NAMPT inhibitor with IC50 value of 5nM. |
| FB10358 | GNE-617 HCl | 2070014-99-0 | GNE-617 HCl is a specific NAMPT inhibitor that inhibits the biochemical activity of NAMPT with an IC50 of 5 nM and exhibits efficacy in xenograft models of cancer. |
| FB00694 | GMX1778 | 200484-11-3 | GMX1778 is a competitive NAMPT (nicotinamide phosphoribosyltransferase) inhibitor. |
| FB03875 | FK866 | 658084-64-1 | FK866 effectively inhibits nicotinamide phosphoribosyltransferase (NMPRTase) with IC50 of 0.09 nM in a cell-free assay. |
| FB04072 | CB-30865 | 206275-15-2 | CB30865 is a potent inhibitor of NAMPT, an enzyme present in the NAD biosynthetic pathway. |
| FB04864 | CB-300919 | 289715-28-2 | CB-300919 is a water-soluble analogue of CB30865, a potent inhibitor of nicotinamide phosphoribosyltransferase (Nampt), and has a continuous exposure(96 h) growth inhibition IC50 value of 2 nM in human CH1 ovarian tumor xenograft. |
| FB11238 | A-1293201 | 1375557-33-7 | A-1293201 is a non-substrate isoindoline urea inhibitors of nicotinamide phosphoribosyltransferase (NAMPT) with nanomolar antiproliferative activity and preclinical pharmacokinetics properties which enabled potent antitumor activity when dosed orally in mouse xenograft models. |