Adrenergic Receptor
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB17768 | Tulobuterol | 41570-61-0 | Tulobuterol (C-78 free base) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol is also a sympathomimetic agent used as a transdermal patch, and increases normal diaphragm muscle strength. |
| FB09826 | Tolazoline HCl | 59-97-2 | Tolazoline HCl is a competitive non-selective α-adrenergic receptor antagonist, used as a a vasodilator directly acting on blood vessels and also increasing cardiac output. |
| FB00173 | Tiamenidine | 31428-61-2 | Thioridazine is an antipsychotic drug, used in the treatment of schizophrenia and psychosis, shows D4 selectivity or serotonin antagonism. |
| FB10241 | Tetrahydrozoline HCl | 522-48-5 | Tetrahydrozoline HCl is an imidazole-derived alpha-adrenergic receptor agonist which can result vasoconstriction and decreased nasal and ophthalmic congestion. |
| FB12708 | ST 1936 Oxalate | 1782228-83-4 | ST1936 oxalate is a selective, nanomolar affinity 5-HT6 receptor agonist with Ki values of 13 nM, 168 nM and 245 nM for human 5-HT6, 5-HT7 and 5-HT2B receptors, respectively. ST1936 oxalate also shows moderate affinity (Ki of 300 nM) for human α2 adrenergic receptor . |
| FB16759 | SR59230A | 174689-39-5 | SR59230A is a potent and selective Adrenergic Receptor β3 antagonist with IC50 values of 40, 408, and 648nM for Adrenergic Receptor β3, β1 and β2, respectively. It shows blood-brain barrier penetrability. |
| FB09820 | Sotalol HCl | 959-24-0 | Sotalol HCl is a competitive non-selective β-adrenergic receptor blocker, used to treat abnormal heart rhythms with elimination half-life of 12 hours. |
| FB15887 | 1-(4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)-2-(2-isopropyl-6-methoxyphenoxy)ethanone hydrochloride | 173059-17-1 | REC-2615 (HCl) is a α1B-adrenoceptor antagonist potentially for the treatment of female sexual dysfunction. |
| FB09000 | Rauwolscine HCl | 6211-32-1 | Rauwolscine hydrochloride is an antagonist of alpha2-adrenergic and partial agonist of 5-HT1A receptor. |
| FB16879 | Propranolol HCl | 3506-09-0 | Propranolol hydrochloride is an antagonist of β-adrenergic. |
| FB01513 | Piribedil | 3605-01-4 | Piribedil is an antiparkinsonian agent and piperazine derivative which acts as a D2 and D3 receptor agonist. |
| FB10288 | Piperoxan HCl | 135-87-5 | Piperoxan HCl is an α2 adrenoceptor antagonist. |
| FB01241 | Oxprenolol HCl | 6452-73-9 | Oxprenolol HCl is an active ingredient that is used in some medicines. The active ingredient is the chemical in a medicine that makes it work. |
| FB00608 | Olodaterol Free Base | 868049-49-4 | Olodaterol is an ultra-long-acting β-adrenoreceptor agonist, role as a bronchodilator agent. |
| FB11515 | Nifenalol HCl | 5704-60-9 | Nifenalol HCl is the hydrochloride of nifenalol which is also known as INPEA and a new beta-adrenergic receptor antagonist. |
| FB02570 | Naphazoline | 835-31-4 | Naphazoline is the common name for 2-(1-naphthylmethyl)-2-imidazoline HCl, it is a sympathomimetic agent with marked alpha adrenergic activity. |
| FB11661 | Metipranolol HCl | 36592-77-5 | Metipranolol is a non-selective β adrenergic receptor blocking agent. |
| FB15343 | METAPROTERENOLSULFATE | 5874-97-5 | Metaproterenol hemisulfate (Orciprenaline hemisulfate) is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist with an IC50 of 68 nM. Metaproterenol hemisulfate also has anti-inflammatory activity[1][2]. |
| FB11820 | LY377604 | 204592-94-9 | LY377604 is a human β3-adrenergic receptor agonist with an EC50 of 2.4 nM and also a β1- and β2-adrenergic receptor antagonist. Ly377604 has been used in trials studying the treatment of Obesity. |
| FB15334 | Lofexidine | 31036-80-3 | Lofexidine is a selective α2-receptor agonist, commonly used to alleviate the physical symptoms of heroin and other types of opioid withdrawal[1][2]. |
| FB04413 | Lofexidine HCl | 21498-08-8 | Lofexidine HCl is an α2A-adrenergic receptor agonist, commonly used to alleviate the physical symptoms of heroin and other types of opioid withdrawal. |
| FB15346 | Landiolol HCl | 144481-98-1 | Landiolol hydrochloride (ONO1101 hydrochloride) is a highly beta1 selective ultra-short acting beta-blocker (β1/β2 selectivity = 255:1, a half-life of 4 min)， acts as an adrenoceptor antagonist[1]. |
| FB07582 | Labetalone HCl | 96441-14-4 | Labetalone hydrochloride is hydrochloride form of labetalone, a blocker of both alpha- and beta-adrenergic receptors that is used as an antihypertensive. |
| FB03139 | Labetalol | 36894-69-6 | Labetalol is an antagonist of α-adrenoreceptor and β-adrenoreceptor that is used for the treatment of high blood pressure. |
| FB12039 | L-765314 | 189349-50-6 | L-765314 is a potent and selective α1b adrenergic receptor antagonist with Kis of 5.4±0.6 nM and 2.0±0.66 nM for rat and human α1b adrenergic receptor, respectively. |
| FB11179 | L-748,337 | 244192-94-7 | L-748337 is a competitive β3-adrenoceptor antagonist that displays selectivity over β1 and β2 receptors (Ki values are 4.0, 204 and 390 nM for β3-, β2- and β1-adrenoceptors respectively). Inhibits cAMP accumulation in response to isoproterenol (IC50 = 6 nM). Reduces iNOS expression, attenuates nitric oxide-induced cell proliferation and induces apoptosis in a melanoma cell line. |
| FB06896 | L-(-)-α-Methyldopa HCl | 884-39-9 | L-(-)-α-Methyldopa HCl is an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive drug used as a sympatholytic or antihypertensive. |
| FB03080 | Isoxsuprine HCl | 579-56-6 | Isoxsuprine is a modulator of β2 adrenoreceptor and has agonist or antagonist effects. |
| FB15349 | Isoproterenol Sulfate Dihydrate | 299-95-6 | Isoproterenol sulfate anhydrous is a useful alkaloid for biological research purposes. |
| FB09819 | Isoprenaline HCl | 51-30-9 | Isoprenaline HCl is an adrenaline structure-related β-adrenergic receptor agonist. |
| FB02844 | Idazoxan HCl | 79944-56-2 | Idazoxan is an alpha2-adrenoceptor antagonist potentially for the treatment of schizophrenia. |
| FB02843 | ICI-118551 | 72795-19-8 | ICI-118551 is a highly selective β2-adrenergic receptor antagonist with Ki values of 0.7, 49.5 and 611 nM for β2, β1 and β3 receptors, respectively. |
| FB10218 | ICI-118551 HCl (Random Configuration) | 1217094-53-5 | ICI-118551 is a highly selective β2-adrenergic receptor antagonist with Ki values of 0.7, 49.5 and 611 nM for β2, β1 and β3 receptors, respectively. |
| FB15289 | GUANABENZ | 5051-62-7 | Guanabenz is an agonist of α2-adrenergic receptor with antihypertensive effect and is enerally used in combination with diuretics. |
| FB09976 | Fenspiride HCl | 5053-08-7 | Fenspiride HCl is an antagonist of α-adrenergic receptors and H1 histamine receptors and also inhibits phosphodiesterase 4 and phosphodiesterase 3 activities with logIC50 values of 4.16 and 3.44, respectively. |
| FB11873 | Fenoterol HCl | 1944-10-1 | Fenoterol HCl is an agonist of β2 adrenoreceptor that is used to open up the airways to the lungs. It is classed as sympathomimetic β2 agonist. |
| FB09808 | Detomidine | 76631-46-4 | Detomidine produce dose-dependent sedative and analgesic effects, is a nonnarcotic, synthetic α2-adrenergic agonist. |
| FB00042 | Clenbuterol HCl | 21898-19-1 | Clenbuterol HCl, a bronchodilator, is an agonist of β2-adrenoceptor that has been used for the treatment of pulmonary diseases such as asthma. |
| FB05151 | CL316243 Disodium Salt | 138908-40-4 | CL-316243 is a potent and highly selective β3-adrenoceptor agonist (EC50 = 3 nM) and > 10000-fold selective over β1 and β2 receptors. CL-316243 restores the expression of down-regulated fatty acid oxidation genes in type 2 diabetic mice. |
| FB11182 | CGP-20712 Methanesulfonate | 105737-62-0 | CGP 20712 methanesulfonate is a highly selective and potent β1-adrenoceptor antagonist (IC50 = 0.7 nM). Displays 10,000-fold selectivity over β2-adrenoceptors. |
| FB11180 | CGP-20712 | 137888-49-4 | CGP 20712 is a highly selective and potent β1-adrenoceptor antagonist (IC50 = 0.7 nM). Displays 10,000-fold selectivity over β2-adrenoceptors. |
| FB11181 | CGP 20712 2HCl | 1216905-73-5 | CGP 20712 2HCl is a highly selective and potent β1-adrenoceptor antagonist (IC50 = 0.7 nM). Displays 10,000-fold selectivity over β2-adrenoceptors. |
| FB10414 | Bopindolol | 62658-63-3 | Bopindolol is a beta blocker. It is an ester which acts as a prodrug for its active metabolite 4-(3-t-butylamino-2-hydroxypropoxy)-2-methylindole. |
| FB11005 | GSK-961081 Succinate | 945905-37-3 | Batefenterol succinate is a muscarinic antagonist and β2-agonist possessing both muscarinic antagonist (MA) and β2-adrenoceptor agonist (BA) properties (MABA). |
| FB09870 | GSK-961081 | 743461-65-6 | Batefenterol is a Muscarinic antagonist and β2-Agonist possessing both muscarinic antagonist (MA) and β2-adrenoceptor agonist (BA) properties (MABA). |
| FB07762 | Apraclonidine HCl | 73218-79-8 | Apraclonidine HCl is a clonidine-derived selective agonist of alpha2-adrenergic receptor. |
| FB11688 | AGN 192836 | 171102-29-7 | AGN 192836 is a potent and selective α2 adrenergic agonist with EC50s of 8.7, 41 and 6.6 nM for α2A, α2B and α2C receptor, respectively. |
| FB17736 | (S)-Viloxazine Hydrochloride | 56287-61-7 | (S)-Viloxazine Hydrochloride is the S-isomer of Viloxazine, a selective norepinephrine reuptake inhibitor (NRI) that can be used as an antidepressant. |
| FB17748 | (R)-Viloxazine Hydrochloride | 56287-63-9 | (R)-Viloxazine Hydrochloride is the R-isomer of Viloxazine, a selective norepinephrine reuptake inhibitor (NRI) that can be used as an antidepressant. |
| FB15306 | Celiprolol HCl | 57470-78-7 |