Human IMP1 (IGF2 mRNA-binding protein 1) originally cloned as ZBP1 [3], is an important RNA-binding protein important for cell RNA localization, migration, stability, and translational control.
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB18845 | MDK6620 | 304456-62-0 | MDK6620 is a potent and selective IMP1 inhibitor by inhibiting IMP1 binding to c-Myc mRNA with IC50 value of 5μM. It downregulates several mRNA transcripts regulated by IMP1, resulting in downregulation of c-Myc mRNA and protein, including c-Myc mRNA, β-TrCP1 mRNA, eEF2 mRNA, as well as reducing activation of NF-κB. |