Beclin 1 (stapled peptide) refers the stapled peptide target Beclin 1.
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB17713 | Tat-SP4 | 2376254-02-1 | Tat-SP4 is an all-hydrocarbon stapled peptide targeting Beclin 1. Tat-SP4 targeted the C-terminal part of the Beclin 1 coiled-coil domain to interfere with its homodimerization, reduced Beclin 1 self-association, promoted Beclin 1–Atg14L/UVRAG interaction, increased autophagic flux, and enhanced EGFR degradation. |