Transthyretin (TTR or TBPA) is a transport protein in the serum and cerebrospinal fluid that carries the thyroid hormone thyroxine (T4) and retinol-binding protein bound to retinol.
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB03528 | Tafamidis | 594839-88-0 | Tafamidis is a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade. |
| FB15767 | Tafamidis meglumine | 951395-08-7 | Tafamidis binds selectively and with negative cooperativity (K(d)s ~2 nM and ~200 nM) to the two normally unoccupied thyroxine-binding sites of the tetramer, and kinetically stabilizes TTR. |