Steroids
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB02503 | α-Estradiol | 57-91-0 | α-Estradiol is an endogenous estrogen receptor ligand (Ki values are 0.2 and 1.2 nM for ERα and ERβ receptors respectively). |
| FB11309 | Withanolide D | 30655-48-2 | Withanolide D is a steroidal lactone isolated from Withania somnifera which exhibits similar cytostatic effect in drug-resistant and drug-sensitive multiple myeloma cells. |
| FB10577 | Uzarigenin Digitaloside | 61217-80-9 | Uzarigenin digitaloside is a natural product isolated and purified from the herbs of Nerium oleander. |
| FB07498 | Timosaponin BII | 136656-07-0 | Timosaponin BII, a natural product isolated and purified from the rhizomes of Anemarrhena asphodeloides Bunge with antioxidant and anti-dementia activities, can inhibit the up-regulation of BACE1 and reduced the over-production of β-CTF and Aβ in rat retina, which was induced by FeCl3, and may be useful for the treatment of type 2 diabetes. |
| FB05551 | Timosaponin A3 | 41059-79-4 | Timosaponin A3, a natural product isolated and purified from the rhizomes of Anemarrhena asphodeloides Bunge, triggers liver injury through inducing ROS generation and suppressing the expression of BA transporters. |
| FB06552 | Tigogenin | 77-60-1 | Tigogenin, a natural product isolated and purified from the herbs of Agave sisalana Perrine, induces apoptosis, associated with overexpression of COX-2 correlated with overproduction of endogenous PGE2, and may modulate differentiation of BMSCs to cause a lineage shift away from the adipocytes and toward the osteoblasts, which is at least mediated by inhibition of PPARgamma and via p38 MAPK pathway. |
| FB06589 | Thevebioside | 114586-47-9 | Thevebioside is a natural glycoside isolated and purified from the herbs of Thevetia neriifolia with cardiac action. |
| FB06466 | Stauntosaponin A | 1417887-91-2 | Stauntosaponin A is a natural product isolated and purified from the herbs of Cynanchum stauntonii (Decne.) Schltr.ex Lev showing moderate inhibitory activities against Na+/K+-ATPase with IC50 values of 21 and 29 uM, respectively. |
| FB05585 | Sprengerinin C | 88861-91-0 | Sprengerinin C, a natural product isolated and purified from the tuber of Ophiopogon japonicus, can strongly suppress tumor angiogenesis in human μMbilical vein endothelial cells. |
| FB06465 | Sprengerinin A | 88866-99-3 | Sprengerinin A is a natural product isolated and purified from the tuber of Ophiopogon japonicus(Thunb.) Ker-Gawl.. |
| FB00526 | Spicatoside B | 87425-34-1 | Spicatoside B is a natural product isolated and purified from Mentha spicata L. |
| FB03724 | Sarsasapogenin | 126-19-2 | Sarsasapogenin, a natural product isolated and purified from the rhizomes of Anemarrhena asphodeloides Bunge with anti-inflammatory, anti-diabetes,antidepressant, antitumor and protective effects, against glutamate-induced neurotoxicity in the cultured cortical neurons in rats, can improve memory by elevating the low muscarinic acetylcholine receptor density in brains of memory-deficit rat models, and effectively promote the proliferation, differentiation and mineralization of osteoblasts cultured in vitro, also inhibit the generation of osteoclasts from marrow cells. |
| FB03724 | Sarsasapogenin | 126-19-2 | Sarsasapogenin, a natural product isolated and purified from the rhizomes of Anemarrhena asphodeloides Bunge with anti-inflammatory, anti-diabetes,antidepressant, antitumor and protective effects, against glutamate-induced neurotoxicity in the cultured cortical neurons in rats, can improve memory by elevating the low muscarinic acetylcholine receptor density in brains of memory-deficit rat models, and effectively promote the proliferation, differentiation and mineralization of osteoblasts cultured in vitro, also inhibit the generation of osteoclasts from marrow cells. |
| FB09134 | Ruscogenin | 472-11-7 | Ruscogenin, a natural product isolated and purified from the root of Ophiopogon japonicus with significant anti-inflammatory and anti-thrombotic activities, significantly attenuates LPS-induced acute lung injury (ALI )via inhibiting expressions of TF and iNOS and NF-κB p65 activation, protects the brain against ischemic damage caused by middle cerebral artery occlusion (MCAO) which may be through downregulation of NF-κB-mediated inflammatory responses, inhibits activation of neutrophil through cPLA 2 , PAK, Akt, MAPKs, cAMP, and PKA signaling pathways, and may attenuate high-fat diet (HFD)-induced steatohepatitis through downregulation of NF- κB-mediated inflammatory responses, reducing hepatic lipogenic gene expression, and upregulating proteins in β-oxidation pathway. |
| FB08126 | Resibufogenin | 465-39-4 | Resibufogenin, a natural product isolated and purified from the glandular body of Bufo bufo gargarizans Cantor, displays great potential as a chemotherapeutic agent in oncology. |
| FB03981 | Pseudobufarenogin | 17008-69-4 | Pseudobufarenogin is a natural compound extracted from toad species with unknown details. |
| FB07500 | Polyphyllin VI | 55916-51-3 | Polyphyllin VI, a natural product isolated and purified from the rhizomes of Paris yunnanensis Franch. with hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy and sperm-killing effects. |
| FB03769 | Polyphyllin II | 76296-72-5 | Polyphyllin II is a natural product isolated and purified from the rhizomes of Paris yunnanensis Franch. with hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy and sperm-killing effects. |
| FB05873 | Neridienone B | 61671-56-5 | Neridienone B is a natural product isolated and purified from the herbs of Nerium indicum Mill. with significant effects on calcein accumulation. |
| FB01995 | Mogroside IIIE | 88901-37-5 | Mogroside IIIE a naturally occuring cucurbitane glycoside which can attenuate gestational diabetes mellitus through activating of AMPK signaling pathway in mice. |
| FB00527 | Liriope Muscari Baily Saponins C | 87480-46-4 | Liriope muscari baily saponins C, a natural product isolated and purified from the roots of Liriope muscari, has an anti-thrombotic activity due to down-regulation of the increased mRNA expression levels of IL-6 and TF. |
| FB07984 | Hecogenin | 467-55-0 | Hecogenin is a natural product isolated and purified from the roots of Aconitum carmichaeli Debx with antioxidant and anti-inflammatory properties, which can protect gastro by K⁺(ATP) channels opening and the COX-2/PG pathway. |
| FB05878 | Glaucogenin C Mono-D-Thevetoside | 849201-84-9 | Glaucogenin C mono-D-thevetoside is a natural product isolated and purified from the roots of Cynanchum stauntonii. |
| FB06125 | Gitogenin | 511-96-6 | Gitogenin, a natural product isolated and purified from the herbs of Agave americana, is a selective inhibitor of UGT1A4, and does not inhibit the activities of major human CYP isoforms. Gitogenin is also an inhibitor of enzyme α-glucosidase with IC50 values of 37.2±0.18 and 33.5±0.22 uM, respectively, and shows moderate stimulation of release activity on growth hormone from rat pituitary cells. |
| FB08159 | Gamabufotalin | 465-11-2 | Gamabufotalin, a major bufadienolide of Chansu, has been used for cancer therapy due to its desirable metabolic stability and less adverse effect. |
| FB05872 | Ergosta-5,24(28)-Diene-3,7,16-Triol | 289054-34-8 | Ergosta-5,24(28)-diene-3,7,16-triol is a natural product isolated and purified from the fruit body of Ganoderma lucidum. |
| FB00121 | Dioscin | 19057-60-4 | Dioscin, a natural product isolated and purified from the rhizome of Dioscorea Zingiberensis C.H.Wright, is a potent ITGA5 inhibitor, showing potent anti-cancer effect against a variety of tumor cell lines. |
| FB04942 | Desacetylcinobufagin | 4026-95-3 | Desacetylcinobufagin is a natural compound used for microbial transformation. |
| FB06460 | Dehydroadynerigenin Glucosyldigitaloside | 144223-70-1 | Dehydroadynerigenin glucosyldigitaloside is a natural product isolated and purified from the herbs of Nerium indicum. |
| FB06462 | Dehydroadynerigenin beta-Neritrioside | 143212-60-6 | Dehydroadynerigenin beta-neritrioside is a natural product isolated and purified from the herbs of Nerium oleander. |
| FB11311 | Degalactotigonin | 39941-51-0 | Degalactotigonin, a natural product isolated and purified from Solanum nigrum L., inhibits growth and metastasis of osteosarcoma through GSK3β inactivation-mediated repression of the Hedgehog/Gli1 pathway. |
| FB05877 | Cynatratoside A | 97399-96-7 | Cynatratoside A is a natural product isolated and purified from the roots of Cynanchum paniculatum, and a potential candidate drug for use against Ichthyophthirius multifiliis. |
| FB06810 | Cyasterone | 17086-76-9 | Cyasterone is an inhibitor of EGFR that maybe a promising anti-cancer agent espcially in skin carcinoma. |
| FB09698 | Cinobufagin | 470-37-1 | Cinobufagin, a natural product isolated and purified from the glandular body of Bufo bufo gargarizans Cantor, inhibits the proliferation and induces apoptosis, may be related to the mitochondria-mediated pathway and GSK-3β/NF-κB pathway, can significantly relieve cancer pain in mice and raised their pain threshold, mainly upregulating the expression levels of β -END and μ -OR in the hind paw tumor and adjacent tissue, and act as a potent anticancer agent against MM and possibly exerts its effects through the ROS-mediated activation of ERK, JNK and p38 MAPK leading to the activation of caspase-3 in U266 cells. |
| FB10846 | Chonglou Saponin VII | 68124-04-9 | Chonglou saponin VII, a natural product isolated and purified from the roots of Paris polyphylla, shows inhibitory effects on cell proliferation. |
| FB10343 | Chenodeoxycholic Acid | 474-25-9 | Chenodeoxycholic acid is a naturally occurring human bile acid, and inhibits production of cholesterol in the liver and absorption in the intestines. |
| FB11184 | Cepa2 | N/A | Cepa2 is a natural product isolated and purified from shallot (Allium cepa L. Aggregatum group) with anticancer activity. |
| FB06463 | Cardenolide B-1 | 1318158-89-2 | Cardenolide B-1 is a natural product isolated and purified from the herbs of Nerium oleander. |
| FB08158 | Bufalin | 465-21-4 | Bufalin a major digoxin-like immunoreactive component of the Chinese medicine Chan Su and has been shown to exert a potential for anticancer activity against various human cancer cell lines in vitro. |
| FB05126 | Arenobufagin | 464-74-4 | Arenobufagin is a natural bufadienolide from toad venom and has potent antineoplastic activity against HCC HepG2 cells as well as corresponding multidrug-resistant HepG2/ADM cells. |
| FB05876 | Adynerigenin beta-Neritrioside | 88721-09-9 | Adynerigenin beta-neritrioside is a natural product isolated and purified from the herbs of Nerium indicum Mill.. |
| FB05874 | 8-Hydroxyodoroside A | 176519-75-8 | 8-hydroxyodoroside A is a natural product isolated and purified from the herbs of Nerium indicum and is a component of antitumor agent. |
| FB05875 | 6-O-Methylcerevisterol | 126060-09-1 | 6-O-Methylcerevisterol is a natural product isolated and purified from the fungus Ganoderma lucidum. |
| FB02668 | 27-Hydroxycholesterol | 20380-11-4 | 27-Hydroxycholesterol is an endogenous oxysterol with multiple biological functions, including activity as a selective estrogen receptor modulator (SERM) (a mixed, tissue-specific agonist-antagonist of the estrogen receptor (ER)) and as an agonist of the liver X receptor (LXR). It is a metabolite of cholesterol that is produced by the enzyme CYP27A1. |
| FB09619 | 20-Hydroxyecdysone | 5289-74-7 | 20-Hydroxyecdysone is a naturally occurring ecdysteroid hormone which controls the ecdysis (moulting) and metamorphosis of arthropods. |
| FB10691 | 20(S)-Ginsenoside Rh2 | 67400-17-3 | 20(S)-ginsenoside Rh2 is a natural product isolated and purified from the root of Panax ginseng C. A. Mey. |
| FB06464 | 2''-O-Acetylsprengerinin C | 1220707-33-4 | 2''-O-acetylsprengerinin C is a natural product isolated and purified from the roots of Ophiopogon japonicus. |
| FB06590 | 17alpha-Thevebioside | 114613-59-1 | 17alpha-Thevebioside is a natural product isolated and purified from the herbs of thevetia neriifolia. |
| FB06461 | 11,12-Di-O-Acetyltenacigenin B | 857897-01-9 | 11,12-Di-O-acetyltenacigenin B is a natural product isolated and purified from the herbs of Marsdenia tenacissima. |