AChR
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB01289 | Varenicline Tartrate | 375815-87-5 | Varenicline tartrate is a nicotinic receptor partial agonist and it stimulates nicotine receptors more weakly than nicotine itself does. |
| FB00880 | Varenicline | 249296-44-4 | Varenicline is a selective α4β2 nicotinic receptor partial agonist and it stimulates nicotine receptors more weakly than nicotine itself does. |
| FB00729 | Trospium Chloride | 10405-02-4 | Trospium chloride is a competitive antagonist at muscarinic cholinergic receptors, used to treat symptoms of an overactive bladder. |
| FB00727 | Tropicamide | 1508-75-4 | Tropicamide is a mAchR M4 antagonist, used to dilate the pupil and help with examination of the eye. |
| FB01094 | Trihexyphenidyl HCl | 52-49-3 | Trihexyphenidyl HCl works as an antiparkinsonian agent which binds to the M1 muscarinic receptor. |
| FB09804 | Tolterodine Tartrate | 124937-52-6 | Tolterodine tartrate is a competitive mAchR antagonist possessing both antimuscarinic and antispasmodic properties. |
| FB09803 | Tolterodine | 124937-51-5 | Tolterodine is a potent muscarinic receptor antagonists that show selectivity for the urinary bladder over salivary glands in vivo. |
| FB09564 | Succinylcholine Chloride Dihydrate | 6101-15-1 | Succinylcholine chloride is a nAchR which acts as a depolarizing neuromuscular blocke, used as a quaternary skeletal muscle relaxant. |
| FB09072 | Rivastigmine Tartrate | 129101-54-8 | Rivastigmine tartrate is an AchR inhibitor use for treatment of mild to moderate Alzheimer's disease and Parkinson's disease with elimination half-life of 1.5 hours. |
| FB08502 | Pyrithioxin | 1098-97-1 | Pyrithioxin is a a nootropic. |
| FB08874 | Pyrithioxin 2HCl | 10049-83-9 | Pyrithioxin 2HCl is a neurodynamic compound, combined with a short period of hyperventilation (HV) was applied in cerebral infarct patients with Hemiplegia. |
| FB08774 | Pyrantel | 15686-83-6 | Pyrantel is a medication used to treat a number of parasitic worm infections. |
| FB08722 | Protriptyline HCl | 1225-55-4 | Protriptyline HCl is a tricyclic antidepressant (TCA), specifically a secondary amine, for the treatment of depression and ADHD. |
| FB08644 | Propantheline Bromide | 50-34-0 | Propantheline bromide is an antimuscarinic agent, used for the treatment of hyperhidrosis, cramps or spasms of the stomach, intestines or bladder, and enuresis. |
| FB06766 | PNU-120596 | 501925-31-1 | PNU-120596 is a a type II positive allosteric modulator of α7 nAChRs with an EC50 of 0.2 μM. |
| FB08410 | Pirenzepine 2HCl | 29868-97-1 | Pirenzepine 2HCl is a is an anticholinergic agent and induces the dimerization of muscarinic M1 receptors, used to treat myopia, gastric and duodenal ulcers. |
| FB08404 | Piperidolate | 82-98-4 | Piperidolate is a muscarinic receptor antagonist which inhibits the action of acetylcholine at postganglionic cholinergic sites. |
| FB08405 | Piperidolate HCl | 129-77-1 | Piperidolate HCl is an antimuscarinic, inhibits intestinal cramp induced by acetylcholine (rats and dogs). |
| FB07956 | Oxybutynin HCl | 1508-65-2 | Oxybutynin HCl a synthetic anticholinergic agent used for treatment of urinary incontinence and overactive bladder syndrome, with elimination half-life of 12.4–13.2 hours. Oxybutynin HCl is the HCl form of Oxybutynin. |
| FB07955 | Oxybutynin | 5633-20-5 | Oxybutynin a synthetic anticholinergic agent used for treatment of urinary incontinence and overactive bladder syndrome, with elimination half-life of 12.4–13.2 hours. |
| FB07599 | Nitenpyram | 150824-47-8 | Nitenpyram is a nAchR agonist, used an antiparasitic drug. |
| FB07421 | Neostigmine Bromide | 114-80-7 | Neostigmine bromide is a cholinesterase inhibitor used in the treatment of myasthenia gravis. Neostigmine bromide is a reversible AchR inhibitor but can not cross the blood-brain barrier. |
| FB04117 | Mepenzolate Bromide | 76-90-4 | Mepenzolate bromide mAchR antagonist, working as a post-ganglionic parasympathetic inhibitor to decrease gastric acid and pepsin secretion and suppresse spontaneous contractions of the colon. |
| FB03385 | Levamisole HCl | 16595-80-5 | Levamisole HCl is a nAChR agonist used as an anthelmintic to treat worm infestations. |
| FB02983 | Ipratropium Bromide' | 22254-24-6 | Ipratropium bromide is a synthetic derivative of the alkaloid atropine anticholinergic properties with anticholinergic properties. |
| FB02495 | Hexamethonium Bromide | 55-97-0 | Hexamethonium bromide is a nicotinic cholinergic antagonist as the prototypical ganglionic blocker. |
| FB02159 | Glycopyrrolate | 596-51-0 | Glycopyrrolate is a muscarinic competitive antagonist used as an antispasmodic. |
| FB02055 | Gallamine Triethiodide | 65-29-2 | Gallamine triethiodide is a competitive cholinergic receptor blocker with an IC50 of 68.0 ± 8.4 μM, used as a non-depolarising muscle relaxant. |
| FB01800 | Flavoxate HCl | 3717-88-2 | Flavoxate HCl is a competitive AChR antagonist with IC50 of 12.2 μM, used as a muscle relaxant. |
| FB01192 | Dronedarone | 141626-36-0 | Dronedarone is a therapeutic agent with a structural resemblance to amiodarone and a better side effect profile and it is a multichannel blocker with antiadrenergic properties and has been evaluated in both rate and rhythm control strategies in the management of AF. |
| FB09468 | Donepezil HCl | 120011-70-3 | Donepezil HCl is a selective and reversible AchE inhibitor, highly selective for the central nervous system and used in the management of mild to moderate Alzheimer's disease and dementia. |
| FB00545 | Diphenidol | 972-02-1 | Diphenidol is indicated in the prevention and symptomatic treatment of peripheral (labyrinthine) vertigo and associated nausea and vomiting that occur in such conditions as Meniere's disease and surgery of the middle and inner ear. |
| FB00838 | Diphenmanil Methylsulfate | 62-97-5 | Diphemanil methylsulfate can bind the muscarinic M3 receptor and decrease secretory excretion of stomach acids and saliva and sweat, as well as works as a direct smooth muscle spasmolytic activity. |
| FB00256 | Decamethonium Bromide | 541-22-0 | Decamethonium bromide is a nAChR partial agonist,working as short acting depolarizing muscle relaxant or neuromuscular blocking agent. |
| FB02175 | Cytisine | 485-35-8 | Cytisine is a naturally occuring alkaloid nAchR agonist with a short half-life of 4.8 hours. |
| FB09194 | Clidinium Bromide | 3485-62-9 | Clidinium bromide is mAchR antagonist used for the symptomatic treatment of peptic ulcer disease and also to help relieve abdominal or stomach spasms or cramps. |
| FB09666 | Cisatracurium Besylate | 96946-42-8 | Cisatracurium besylate is an antagonize of AchR and inhibits neuromuscular transmission, a nondepolarizing skeletal muscle relaxant. |
| FB09396 | Cevimeline | 107233-08-9 | Cevimeline is a parasympathomimetic and muscarinic agonist, with particular effect on M3 receptors and used in the treatment of dry mouth associated with sjogren's syndrome. |
| FB09181 | Carbetapentane Citrate | 23142-01-0 | Carβpentane citrate is a selective inhibitor of mAchR with Ki value of 76nM, also binds to serotonin 5-HT3 with Ki value of 7.9 nM and works as an agonist of the sigma-1 receptor (Ki = 10.4 nM). |
| FB09164 | Camylofine | 54-30-8 | Camylofine is an antimuscarinic and a smooth muscle relaxant. |
| FB08289 | Biperiden | 514-65-8 | Biperiden is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker. |
| FB08290 | Biperiden HCl | 1235-82-1 | Biperiden HCl is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker. |
| FB08239 | Bethanechol | 674-38-4 | Bethanechol is a parasympathomimetic choline carbamate that selectively stimulates muscarinic receptors without any effect on nicotinic receptors. |
| FB08240 | Bethanechol Chloride | 590-63-6 | Bethanechol chloride is a selective mAchR receptor agonist as a parasympathomimetic choline carbamate. |
| FB09346 | Benztropine Mesylate | 132-17-2 | Benztropine mesylate is a central muscarinic antagonist and a DAT inhibitor with IC50 of 118 nM, indicated for symptomatic relief of parkinsonism and drug-induced extrapyramidal reactions. |
| FB07804 | Arecoline Hydrobromide | 300-08-3 | Arecoline hydrobromide is a mAchR receptor agonist with EC50 values of 7, 95, 11, 410, and 69 nM for M1, M2, M3, M4, and M5, respectively, a nicotinic acid-based alkaloid found in the areca nut. |
| FB07803 | Arecaidine But-2-Ynyl Ester Tosylate | 499-04-7 | Arecaidine but-2-ynyl ester tosylate is a potent muscarinic agonist that shows 4.6-fold that is selectivity for mAChR M2 in the atrium versus those in the ileum. |
| FB10628 | Anisodamine | 55869-99-3 | Anisodamine is an inhibitor of alpha-1 adrenergic receptors and mAChRs isolated from Chinese solanacea plant. |
| FB05353 | (R)-Fesoterodine Fumarate | 286930-03-8 | (R)-Fesoterodine fumarate is an antimuscarinic agent and is rapidly de-esterified to its active metabolite 5-hydroxymethyl tolterodine that is a muscarinic receptor antagonist. |
| FB02655 | (R)-5-Hydroxymethyl Tolterodine | 207679-81-0 | (R)-5-Hydroxymethyl tolterodine is a potent and selective muscarinic receptor antagonist with a Kb and a pA2 of 0.84 nM and 9.14, respectively. |