CAS:1508-65-2Oxybutynin hydrochloride

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Oxybutynin HCl 盐酸奥昔布宁 Cat No. FB07956Cas No. 1508-65-2

Oxybutynin HCl a synthetic anticholinergic agent used for treatment of urinary incontinence and overactive bladder syndrome, with elimination half-life of ‎12.4–13.2 hours. Oxybutynin HCl is the HCl form of Oxybutynin.

规格	价格	促销价格	库存

18817579266

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18817579266

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实验数据

储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.5384 mL
- 12.6920 mL
- 25.3841 mL
- 5 mM
- 0.5077 mL
- 2.5384 mL
- 5.0768 mL
- 10 mM
- 0.2538 mL
- 1.2692 mL
- 2.5384 mL
计算器摩尔计算器总药量计算器工作液计算器

技术信息

CAS号

1508-65-2

储存条件

粉末: -20°C 3 年

液体: -80°C 12 月

分子式

C22H32ClNO3

运输

蓝冰

分子量

393.95

别名

溶解度

DMSO	220.0 mg/mL (558.5 mM)
Water	88.0 mg/mL (223.4 mM)

动物实验配方

靶点数据

生物活性

描述Oxybutynin HCl is an anticholinergic agent. Oxybutynin inhibited vascular Kv channels in a concentration-dependent manner, with an IC50 value of 11.51 ± 0.38 μmol/L and a Hill coefficient (n) of 2.25 ± 0.12. Oxybutynin inhibited the vascular Kv current in a concentration-dependent manner by influencing the steady-state activation and inactivation curves independent of its anticholinergic effect^[3]. The majority of the patients (88.2%) with IBSF (inadequate bladder storage function) were responsive to the 15-mg daily oxybutynin HCl. Oxybutynin HCl in sufficient dosages seems to be effective in the treatment of enuretic patients with IBSF^[4]. Oxybutynin seems promising in the management of hot flashes with tolerable side effects in the majority of refractory patients^[5]. Oxybutynin 3% gel reduced hyperhidrosis severity and improved health-related quality of life in this small pilot study^[6].