Alkaloids
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB04404 | Xanthine | 69-89-6 | Xanthine is a natural occuring purine-base adenosine receptor antagonist, from which a number of stimulants such as caffeine and theobromine are derived. |
| FB06214 | Veratramine | 60-70-8 | Veratramine is a natually occuring alkaloid isolated from the rhizomes of Veratrum and can inhibit the Hh signaling-dependent proliferation of NIH/3T3 cells for it is an analog of cyclopamine. |
| FB02953 | Tuberostemonine | 6879-01-2 | Tuberostemonine is a natural product isolated from the roots of Stemona japonica, which shows therapeutic effects against cigarette smoke-induced acute lung inflammation in mice and acts as an open-channel blocker at the crayfish neuromuscular junction. |
| FB00501 | Trigonelline | 535-83-1 | Trigonelline, a natural product isolated and purified from the seeds of Trigonella foenum-graecum L. with phytoestrogenic and antitumor effects, inhibits the adipogenesis by its influences on the expression PPARγ, which leads to subsequent down regulation of PPAR-γ mediated pathway during adipogenesis. |
| FB00272 | Triacetonamine HCl | 33973-59-0 | Triacetonamine HCl is a natural product isolated and purified from the senescing flag leaves of the barley varieties Lomerit and Carina and an anticancer chemotherapeutic agent. |
| FB12969 | Thymidine | 50-89-5 | Thymidine, a constituent of DNA, pairs with adenine and attach to the sugar deoxyribose in the DNA double helix. |
| FB04182 | Theobromine | 83-67-0 | Theobromine, a xanthine alkaloid isolated and purified from the fruits of Theobroma cacao L., is widely consumed as stimulants and snacks in coffee and cocoa based foods and most often as part of ingredients in drugs. |
| FB10849 | Tetrahydroepiberberine | 38853-67-7 | Tetrahydroepiberberine is a natural product isolated and purified from the herbs of Sinomenium acutum. |
| FB02190 | Tenuazonic Acid | 610-88-8 | Tenuazonic acid is an active component in the A. alternata toxin. |
| FB09483 | Sophoridine | 6882-68-4 | Sophoridine is naturally occuring alkaloid found in the plant Sophora flavescens, which could suppresses cell growth of human medulloblastoma through the inhibition of the FoxM1, NF‑κB and AP‑1 signaling pathway. |
| FB04233 | Solasonine | 19121-58-5 | Solasonine is a natural product isolated and purified from the herbs of Solanum nigrum L. |
| FB10613 | SN-38 | 86639-52-3 | SN-38 is an active metabolite of CPT-11 that inhibits DNA topoisomerase I, DNA synthesis and causes frequent DNA single-strand breaks. |
| FB06628 | Skimmianin | 83-95-4 | Skimmianin, a natural product isolated and purified from the herbs of Skimmia japonica, is an inhibitor against the Leishmania APRT enzyme and a strong acetylcholinesterase (AChE) inhibitor, and has a selective inhibitory effect on the 5-hydroxytryptamine-induced vasopressor responses of rats. |
| FB06628 | Skimmianin | 83-95-4 | Skimmianin, a natural product isolated and purified from the herbs of Skimmia japonica, is an inhibitor against the Leishmania APRT enzyme and a strong acetylcholinesterase (AChE) inhibitor, and has a selective inhibitory effect on the 5-hydroxytryptamine-induced vasopressor responses of rats. |
| FB07554 | Sinoacutine | 4090-18-0 | Sinoacutine is a natural product isolated and purified from the roots of Stephania epigaea Lo. |
| FB09255 | Senecionine | 130-01-8 | Senecionine is a pyrrolizidine alkaloid isolated from Senecio vulgaris. Senecionine is toxic to animals and humans. |
| FB00429 | Protopine | 130-86-9 | Protopine is a naturally occuring benzylisoquinoline alkaloid found in plants of the family papaveraceae. It acts as an analgesic and can inhibit histamine H1 receptors. |
| FB09323 | Phellodendrine HCl | 104112-82-5 | Phellodendrine HCl, a natural product isolated and purified from the cortex Phellodendri chinensis with anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli. |
| FB00219 | Nicotinic Acid | 59-67-6 | Nicotinic acid is a water-soluble vitamin and is part of the vitamin B group. |
| FB07632 | N-Methylcytisine | 486-86-2 | N-Methylcytisine's nicotinic receptors have high affinity (KD = 50 nM)to nAChR from squid optical ganglia. |
| FB07337 | Mesaconitine | 2752-64-9 | Mesaconitine is the main active component of genus aconitum plants. |
| FB08358 | Melatonin | 73-31-4 | Melatonin is a hormone which plays a role in natural sleep-wake cycle and also a ATF6 blocker. |
| FB02964 | Magnoflorine Chloride | 6681-18-1 | Magnoflorine is a natural product isolated and purified from the flower of Magnolia liliiflora Desr. with anti-inflammatory activity. |
| FB12811 | L-carnosine | 305-84-0 | L-carnosine is an antioxidant naturally found in skeletal muscle, brain tissue, and the heart, it can scavenge oxygen free radicals and transition metal ions, block protein-protein and protein-DNA cross-links induced by hypochlorite anions and toxic aldehydes, inhibit nonenzymatic protein glycation induced by aldose and ketose reducing sugars and inhibit the formation of toxic advanced glycation end products (AGE). |
| FB07263 | Jatrorrhizine | 3621-38-3 | Jatrorrhizine is a protoberberine alkaloid isolated from some plant species like Enantia chlorantha. It can inhibit MAO-A and MAO-B noncompetitively with IC50 value of 4μM and 62μM, respectively. Also, it has antiinflammatory, antimicrobial and antifungal activity. |
| FB07343 | Jatrorrhizine HCl | 6681-15-8 | Jatrorrhizine HCl is a protoberberine alkaloid isolated from some plant species like Enantia chlorantha. It can inhibit MAO-A and MAO-B noncompetitively with IC50 value of 4μM and 62μM, respectively. Also, it has antiinflammatory, antimicrobial and antifungal activity. |
| FB00314 | Isofangchinoline | 33889-68-8 | Isofangchinoline is a bisbenzyltetrahydroisoquinoline alkaloid isolated from Stephania tetrandra, which may be an inactivator of nuclear NR4A1, as well as inhibited cell proliferation and induced apoptosis in human pancreatic cancer cells. |
| FB12979 | Indole-3-carboxylic acid | 771-50-6 | Indole-3-carboxylic Acid is a normal urinary indolic tryptophan metabolite with multiple biological roles such as serotonin 5-HT4/6 receptor antagonist, EphB3 receptor tyrosine kinase inhibitor, vinyl ester pseudotripeptide proteasome inhibitor and potential therapeutic agent for Alzheimer′s Disease. |
| FB10432 | Hypoxanthine | 68-94-0 | Hypoxanthine, a naturally occurring purine derivative, an intermediate product of uric acid synthesis, formed from adenylic acid and itself a precursor of xanthine. |
| FB07325 | Hypaconitine | 6900-87-4 | Hypaconitine, an active and highly toxic constituent derived from Aconitum species, is widely used to treat rheumatism. |
| FB10609 | Huperzine A | 102518-79-6 | Huperzine A is a naturally occurring sesquiterpene alkaloid AChE inhibitor. |
| FB01044 | Homoharringtonine | 26833-87-4 | Homoharringtonine is a cytotoxic alkaloid from the evergreen tree. |
| FB02525 | Hirsutine | 7729-23-9 | Hirsutine, an indole alkaloid isolated and purified from the herbs of Uncaria rhynchophylla, which can inhibits Late step in dengue virus lifecycle. |
| FB01212 | Harringtonine | 26833-85-2 | Harringtonine is a natural alkaloid isolated and purified from the branch of Cephalotaxus fortunei Hook.f., and an anticancer drug with high chemotherapeutic efficiency to human chronic granulocytic/myelomonocytic leukemia, has been reported to rapidly induce apoptosis in HL-60 cells in a wide scope/range of dosage by investigators from our lab and others. Harringtonine exerts its antiviral effects by inhibiting Chikungunya virus (CHIKV) viral protein synthesis. |
| FB07218 | H-Cit-OH | 372-75-8 | H-Cit-OH is a natural product isolated and purified from the herbs of Citrullus lanatus. |
| FB06269 | Foresaconitine | 73870-35-6 | Foresaconitine is a norditerpenoid alkaloid isolated from the processed tubers of Aconitum carmichaeli. |
| FB03321 | Evodiamine | 518-17-2 | Evodiamine, a natural product isolated and purified from the fruits of Evodia rutaecarpa (Juss.) Benth. with anti-oxidation, anti-inflammatory and anti-cancer effects, is an apoptosis inducer via the AKT pathway and an inhibitor of cancer cells proliferation via inhibition of MTDH expression and activation of apoptosis. |
| FB10312 | Epiberberine Chloride | 889665-86-5 | Epiberberine chloride, a natural alkaloid, is a BACE1 inhibitor, which also exhibits inhibition activity on CYP2D6 and aldose reductase, alpha-adrenoceptors, acetylcholinesterase (AChE), butyrylcholinesterase, and b-site amyloid precursor protein cleaving enzyme 1. |
| FB09932 | Crotonoside | 1818-71-9 | Crotonoside is a naturally occurring active isomer of guanosine found in the seeds of Croton tiglium, which could reduce the blood pressure in rabbits and cats. |
| FB06209 | Coptisine Chloride | 6020-18-4 | Coptisine Chloride is a naturally occuring cytotoxic alkaloid found in Chinese goldthread which shows cytotoxic effect on heptoma and leukemic cells and is reported to block cell cycle progression. |
| FB09400 | Chelerythrine | 34316-15-9 | Chelerythrine, a natural product isolated and purified from the herbs of Chelidonium majus with potent antimanic, antiproliferatvie and antitumor effect, can inhibit telomerase activity, and is a well-known protein kinase C inhibitor. |
| FB06694 | Cepharanthine | 481-49-2 | Cepharanthine is a naturally occurring alkaloid extracted from the plant Stephania cepharantha Hayata. It possesses potency of antiinflammatory, antineoplastic and effect against HTLV. |
| FB11310 | Capnoidine | 485-50-7 | Capnoidine is an isoquinoline alkaloid isolated and purified from Corydalis impatiens (Pall.) Fisch. |
| FB00813 | Berberrubine | 15401-69-1 | Berberrubine, a natural product isolated and purified from the herbs of Coptis chinensis Franch. with antitumor and antidiabetic activity, dose-dependently inhibits IL-8 and MCP-1 protein levels in the media and mRNA expression of the cells stimulated with IL-1beta or TNF-alpha. |
| FB06222 | Benzoylhypaconine | 63238-66-4 | Benzoylhypaconine is a natural product. |
| FB08029 | 4-Amino-4-Methyl-2-Pentanone | 625-04-7 | 4-amino-4-methyl-2-pentanone is a natural product isolated and purified from soyben curd. |
| FB13015 | 3-(2-Hydroxyethyl)indole | 526-55-6 | 3-(2-Hydroxyethyl)indole is an aromatic alcohol participate in many biological reactions. |
| FB07539 | 3,4-Dimethoxybenzamide | 1521-41-1 | 3,4-Dimethoxybenzamide is a natural product isolated and purified from the leaves of Litsea costalis (Nees) Kosterm.. |
| FB06613 | 14-Norpseurotin A | 1031727-34-0 | 14-Norpseurotin A is a natural product isolated and purified from the cultures of Aspergillus fumigatus, shows good antileishmanial and moderate anticancer activities, significantly induces neurite outgrowth of rat pheochromocytoma cells (PC12) at a 10.0 microM concentration, and displays significant antimicrobial activities against Escherichia coli, Bacillus subtilis, and Micrococcus lysoleikticus with MICs of 3.74, 14.97, and 7.49 mM , respectively. |
| FB08445 | (+)-Matrine | 519-02-8 | (+)-Matrine is a naturally occuring κ-opioid and μ-opioid receptor agonist. |