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Fraxinellone, a natural product isolated and purified from the root barks of Dictamnus dasycarpus Turcz. with neuroprotective, vasorelaxing, insecticidal, and antimicrobial activities, is a selective blocker of voltage-dependent Ca2+ channel, while dictamine relaxed the rat aorta by suppressing the Ca2+ influx through both voltage-dependent and receptor-operated Ca2+ channels, and can dramatically induce apoptosis of activated peripheral CD4(+) T cells in vivo, consequently resulting in less CD4(+) T-cell activation and infiltration to the liver.
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18817579266
实验数据
技术信息
CAS号 | 28808-62-0 | 储存条件 |
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分子式 | C14H16O3 | 运输 | 蓝冰 | |||
分子量 | 232.28 | 别名 | ||||
溶解度 |
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动物实验配方 |
生物活性