Alkaloids

Alkaloids

货号 产品名 CAS号 信息
FB00912 Vitamin B1 59-43-8 Vitamin B1 is a water-soluble vitamin, as are all vitamins of the B complex.
FB00897 Vinpocetine 42971-09-5 Vinpocetine is a selective inhibitor for PDE1 with IC50 of 21 μM, it also blocks voltage-gated Na+ channels. It's a natural product isolated and purified from the herbs of Catharanthus roseus (L.) G. Don.
FB00895 Vinorelbine 71486-22-1 Vinorelbine is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM.
FB00892 Vincamine 1617-90-9 Vincamine is a nootropic monoterpenoid indole alkaloid found in the leaves of Vinca minor (lesser periwinkle), which is used as a memory enhancing prescription medicine for the treatment of primary degenerative and vascular dementia.
FB00882 Vasicinone 486-64-6 Vasicinone, a natural product isolated and purified from the herb of Peganum harmala L., may act as a hepatoprotective agent, which has significant antitussive, expectorant, and bronchodilating activities and exhibits antiproliferative activity against human gastric cancer cells MCG-803.
FB00967 Vasicinolone 84847-50-7 Vasicinolone, a natural product isolated and purified from the leaves of Adhatoda vasica, has anti-inflammatory and antimicrobial activity.
FB10506 Vasicine 6159-55-3 Vasicine, a natural product isolated and purified from the leaves of Adhatoda vasica, is a potential cholinesterase inhibitor in development for treatment of Alzheimer's disease, and can regulate the inflammatory reaction.
FB00065 Tetrahydroberberine 522-97-4 Tetrahydroberberine is an isoquinoline alkaloid isolated and purified from the barks of Phellodendron chinense Schneid. It has micromolar affinity for dopamine D(2) (pK (i) = 6.08) and 5-HT(1A) (pK (i) = 5.38) receptors but moderate to no affinity for other relevant serotonin receptors(5-HT(1B), 5-HT(1D), 5-HT(3), and 5-HT(4); pK (i) < 5.00).
FB00064 Tetrahydroalstonine 6474-90-4 Tetrahydroalstonine, a natural product isolated and purified from the herbs of Uncaria rhynchophylla (Miq.) Miq. ex Havil., preferentially blocks the pressor responses of post-synaptic alpha-adrenergic receptor activation due to exogenous and endogenouse noradrenaline, respectively.
FB09645 Tabersonine 4429-63-4 Tabersonine, a natural product isolated and purified from the root bark of Voacanga africana Stapf, is a precursor for vincristine used in cancer chemotherapy, the biocompatibility and small size essential for permeating the blood-brain barrier make it a potential therapeutic drug candidate for treating AD.
FB09569 Sudan III 85-86-9 Sudan III is predominantly used for staining triglycerides in animal tissues (frozen sections).
FB09526 Stachydrine HCl 4136-37-2 Stachydrine HCl is a naturally occuring anti-metastatic agent in vitro which is isolated from seed husk and the pulp of the fruit of C. Leonurus.
FB09486 Sparteine Sulfate Pentahydrate 299-39-8 Sparteine sulfate is a natural product isolated and purified from the herbs of Parochetus communis.
FB09480 Solasodine 126-17-0 Solasodine is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family.
FB09334 Sinomenine HCl 6080-33-7 Sinomenine Hydrocloride is a an alkaloid found in the root of the climbing plant Sinomenium acutum which has anti-inflammatory effects in several animal models of inflammation and inhibits mast cell degranulation and histamine release. It is used to treat inflammatory diseases like rheumatoid arthritis.
FB09259 Serpentine 18786-24-8 Serpentine is a natural product isolated and purified from the herbs of Rauvolfia yunnanensis.
FB09256 Seneciphylline 480-81-9 Seneciphylline, a natural product isolated and purified from the herbs of Senecio scandens, can significantly increased the activities of epoxide hydrase and glutathione-S-transferase but cause reduction of cytochrome P-450 and related monooxygenase activities.
FB09213 Scoulerine 6451-73-6 Scoulerine, a natural product isolated and purified from the herbs of Corydalis dubia., shows significant cytotoxic effects against both two cancer cell lines (Caco-2 and Hep-G2 cancer cells), with IC50 values 6.44 ± 0.87 and 4.57 ± 0.42, respectively.
FB10722 Sanguinarine Chloride 5578-73-4 Sanguinarine chloride is a naturally occuring benzophenanthridine alkaloid which can inhibit sodium/potassium-ATPase protein (Na+/K+ ATPase) and cause Epidemic dropsy.
FB09060 Rhynchophylline 76-66-4 Rhyncholphylline, an alkaloid isolated and purified from the herbs of Uncaria rhynchophylla., can protect against ischemic damage and glutamate-induced neuronal death, and also inhibit MA impairment in cultured neurons in vitro.
FB09010 Rhodamine B 81-88-9 Rhodamine B is used in biology as a staining fluorescent dye, applied in fluorescence microscopy, flow cytometry, fluorescence correlation spectroscopy and ELISA.
FB08527 Pramipexole 2HCl 104632-25-9 Pramipexole 2HCl is an dopamine agonist and can inhibit multiple dopamine receptors including dopamine D2S receptor, dopamine D2L receptor, dopamine D3 receptor, and dopamine D4 receptor with respectively Ki values of 3.9, 2.2, 0.5 and 5.1 nM.
FB08406 Piperlongumine 20069-09-4 Piperlongumine, a natural alkaloid from Piper longum L., increases the level of reactive oxygen species (ROS) and selectively kills cancer cells. It is a direct TrxR1 inhibitor with suppressive activity against gastric cancer and an inhibitor of CRM1 and is also an inhibitor of PI3K/Akt/mTOR in human breast cancer cells.
FB05330 Piperine 94-62-2 Piperine is a major alkaloid isolated from the P. longum fruits which possesses anti-inflammatory and antiarthritic effects.
FB08359 Physostigmine 57-47-6 Physostigmine is also reported to form a slowly degrading carbamylated enzyme complex with AChE (acetylcholinesterase).
FB07989 Palmatine 3486-67-7 Palmatine, a natural product isolated and purified from the rhizomes of Coptis chinensis Franch., is an inhibitor of dopamine generation. Palmatine could potentially be developed for the treatment of flavivirus infections.
FB07961 Oxysophocarpine 26904-64-3 Oxysophocarpine, a natural product isolated and purified from the root of Styphnolobium japonicum (L.) Schott., can decrease the level of serum transaminase, improve lipid metabolism, reduce synthesis of inflammatory cytokines TNF-α, TGF-β1 and IL-6, activate protective adipocytokine adiponectin, and may be a drug for colonic inflammation and NASH.
FB07764 Nuciferine 475-83-2 Nuciferine is naturally occuring alkaloid found in the plants Nymphaea caerulea and Nelumbo nucifera as a potent inverse agonist at human 5-HT7 receptor.
FB10519 Norepinephrine 51-41-2 Norepinephrine is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter, effective for maintaining blood pressure and was associated with greater heart rate and cardiac output compared with phenylephrine.
FB07412 Neferine 2292-16-2 Neferine, is a major alkaloid present in the green embryos of Nelumbo nucifera Gaertn with anti-arrhythmia, anti-hypertensive and vaso-relaxant properties , and is also a NF-κB inhibitor.
FB10484 N-Methyl-L-Tryptophan 526-31-8 N-Methyl-L-tryptophan, a natural product isolated and purified from the seeds of Abrus precatorius, show comparable ABTS radical cation scavenging activities and reducing power to two commercial antioxidants (BHT and Trolox).
FB06541 Myricitrin 17912-87-7 Myricitrin, a flavonoid compound isolated from the root bark of Myrica cerifera, which exerts antinociceptive effects.
FB06324 Monocrotaline 315-22-0 Monocrotaline is a naturally occuring pyrrolizidine alkaloid which can cause pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature.
FB03754 Lycorine 476-28-8 Lycorine, a natural product isolated and purified from the bulbus of Lycoris radiata (L. Herit.) Herb, has anti-cancer effect that dependent on STAT expression.
FB03538 Leonurine 24697-74-3 Leonurine is a pseudoalkaloid possessing anti-inflammatory properties and isolated from plants of family Lamiaceae.
FB10482 Laurolitsine 5890-18-6 Laurolitsine is a natural product isolated and purified from the roots of Lindera aggregata (Sims) Kosterm.
FB03338 Lappaconitine Hydrobromide 97792-45-5 Lappaconitine hydrobromide, a diterpene alkaloid, is a drug for the treatment of cardiac arrhythmias.
FB03047 Isotetrandrine 477-57-6 Isotetrandrine, a natural product isolated and purified from the roots of Stephania tetrandra S.Moore, dose-dependently suppresses the severity of LPS-induced ALI by inactivation of MAPK and NF-κB, which may involve the inhibition of tissue oxidative injury and pulmonary inflammatory process.
FB10491 Harmine 442-51-3 Harmine is a naturally occuring fluorescent harmala alkaloid isolated plants like Middle Eastern plant harmal which can reversibly inhibit MAOA.
FB06671 Glaucine 475-81-0 Glaucine, a natural product isolated and purified from the tubers of Corydalis yanhusuo, can inhibit the migration and invasion of human breast cancer cells by MMP-9 inhibitory activity, attenuating IκBα and NF-κB activities.
FB09123 Fumitremorgin C 118974-02-0 Fumitremorgin C is a chemosensitizing agent which selectively reverses BCRP-mediated multidrug resistance to mitoxantrone, doxorubicin and topotecan in transfected MCF-7 cells, but does not reverse resistance in P-gp- or MRP-positive cells.
FB05544 Dihydrocapsaicin 19408-84-5 Dihydrocapsaicin, a natural product isolated and purified from the fruits of Capsicum annuum L..
FB01697 Dehydroevodiamine 67909-49-3 Dehydroevodiamine is an alkaloid isolated from E. rutaecarpa and possesses anti-inflammatory, antiarrhythmic, hypotensive, and anti-amnesic biological activities.
FB06994 Cephalotaxine 24316-19-6 Cephalotaxine is a benzazepine alkaloid isolated from Cephalotaxus harringtonia with function of antiviral and antitumor.
FB07586 Berberine HCl 633-65-8 Berberine HCl is an isoquinoline alkaloid isolated from the herb of Coptis chinensis Franch with anti-inflammatory and anti-diabetic effects.
FB10532 5-Hydroxytryptophan 56-69-9 5-Hydroxytryptophan is a naturally occurring amino acid which acts as a chemical precursor as well as a metabolic intermediate in the biosynthesis of the neurotransmitter serotonin.
FB02932 3-Hydroxy-3-Acetonyloxindole 33417-17-3 3-Hydroxy-3-acetonyloxindole is a natural product isolated and purified from the herbs of Marsdenia tinctoria.
FB00972 3-Furfuryl 2-Pyrrolecarboxylate 119767-00-9 3-Furfuryl 2-pyrrolecarboxylate is a natural product isolated and purified from the roots of Pseudostellaria heterophylla.
FB00993 2,4,6,6-Tetramethyl-3(6H)-Pyridinone 203524-64-5 2,4,6,6-Tetramethyl-3(6H)-pyridinone is a natural product isolated and purified from the herbs of Sophora viciifolia.
FB00981 1,3-Dihydroxy-4-Methoxy-10-Methylacridin-9(10H)-One 1189362-86-4 1,3-Dihydroxy-4-methoxy-10-methylacridin-9(10H)-one is a natural product isolated and purified from the stem bark of mMelum hirsutum.
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