AChR
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB02584 | Xanomeline | 131986-45-3 | Xanomeline is a functionally selective M1/M4 agonist, used in the study of both Alzheimer's disease and schizophrenia. |
| FB05733 | Varenicline HCl | 230615-23-3 | Varenicline HCl is a nicotinic receptor partial agonist and it stimulates nicotine receptors more weakly than nicotine itself does. |
| FB10735 | TBPB | 634616-95-8 | TBPB is an allosteric M1 mAChR agonist (EC50=289 nM) that regulates amyloid processing and produces antipsychotic-like activity in rats. |
| FB07069 | Scopolamine Butylbromide | 149-64-4 | Scopolamine butylbromide is a muscarinic antagonist used to treat crampy abdominal pain, esophageal spasms, renal colic, bladder spasms and improve respiratory secretions at the end of life. |
| FB04212 | Procaine HCl | 51-05-8 | Procaine HCl is a local anesthetic drug of the amino ester group. |
| FB11234 | PPBI | 959863-94-6 | PPBI is a tool compound and an agonist of M1 muscarinic receptor. |
| FB08049 | Pipenzolate Bromide | 125-51-9 | Pipenzolate bromide is an antimuscarinic. It binds to muscarinic acetylcholine receptors as an antagonist therefore preventing acetylcholine from binding to the receptors. |
| FB08371 | Pilocarpine Nitrate | 148-72-1 | Pilocarpine nitrate is a non-selective muscarinic receptor agonist, a parasympathomimetic alkaloid, a drug used to treat glaucoma. |
| FB02598 | Pilocarpine HCl | 54-71-7 | Pilocarpine HCl is a nonselective muscarinic acetylcholine receptor agonist used to produce an experimental model of epilepsy. |
| FB04225 | Methscopolamine Bromide | 155-41-9 | Methscopolamine is a mAchR antagonist structurally similar to the neurotransmitter acetylcholine. |
| FB07560 | L-Nicotine | 54-11-5 | L-Nicotine is the prototype of nicotinic acetylcholine receptor agonists. |
| FB03424 | L-Hyoscyamine | 101-31-5 | L-Hyoscyamine is a chemical compound, a tropane alkaloid it is the levo-isomer to atropine. It is also an AChR inhibitor with IC50 of 7.5 nM. |
| FB02555 | Homatropine Methylbromide | 80-49-9 | Homatropine methylbromide is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively. |
| FB02554 | Homatropine Bromide | 51-56-9 | Homatropine bromide is an muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 170.3 nM, respectively. |
| FB08499 | Carbamoylcholine Chloride | 51-83-2 | Carbamoylcholine chloride is used to study responses mediated by nAChR and mAChR, including smooth muscle contraction, gut motility, and neuronal signaling. |
| FB03887 | Benzethonium Chloride | 121-54-0 | Benzethonium chloride can inhibit nAChRs with IC50 values of 49 nM and 122 nM for α4β2 nAChRs and α7 nAChRs, respectively. It is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties. |
| FB00099 | Atropine Sulfate Monohydrate | 5908-99-6 | Atropine Sulfate Monohydrate is one kind of anticholinergics working by blocking the actions of acetylcholine, use for a medication to treat certain types of nerve agent. |
| FB10629 | Atropine Sulfate | 55-48-1 | Atropine sulfate is one kind of anticholinergics working by blocking the actions of acetylcholine, use for a medication to treat certain types of nerve agent. |
| FB07390 | Aclidinium Bromide | 320345-99-1 | Aclidinium bromide is a long-acting, inhaled muscarinic antagonist as a maintenance treatment for chronic obstructive pulmonary disease (COPD). |
| FB07258 | Acetylcholine Iodide | 2260-50-6 | Acetylcholine iodide is an ester of choline and acetic acid, which acts as a transmitter substance of nerve impulses within the central and peripheral nervous systems. |
| FB07257 | Acetylcholine Chloride | 60-31-1 | Acetylcholine chloride is a neurotransmitter that can induce the opening of calcium channels. |
| FB05545 | (-)-Scopolamine Hydrobromide | 114-49-8 | (-)-Scopolamine hydrobromide is a competitive muscarinic acetylcholine receptor (mAChR) with an IC50 of 55.3 ± 4.3 nM. |