| FB07849 |
α-Spinasterol
|
481-18-5 |
α-Spinasterol is an efficacious and safe antagonist of the TRPV1 receptor with antinociceptive effect. |
| FB06340 |
SAR7334 2HCl
|
1333207-63-8 |
SAR7334 2HCl is a potent and specific TRPC6 inhibitor, inhibiting TRPC6 currents with IC50 of 7.9 nM. |
| FB08570 |
Probenecid
|
57-66-9 |
Probenecid inhibits TRP channels such as TRPV2, TRPM8 and TRPA1. It is an inhibitor of the renal excretion of organic anions. |
| FB03867 |
PF-4840154
|
1332708-14-1 |
PF-4840154 is a potent, selective agonist of the rat and human TrpA1 channel and elicited TrpA1-mediated nocifensive behaviour in mouse, with EC50 of 97 nM and 23 nM for rTrpA1 and hTrpA1, respectively. |
| FB11120 |
Cryosim-3
|
1507344-37-7 |
Cryosim-3 is a selective and potent TRPM8 agonist without TRPV1 or TRPA1 activity, and a promising candidate for study of TRPM8 function on the eye surface and for relief of dry eye discomfort. |
| FB09173 |
Capsazepine
|
138977-28-3 |
Capsazepine is an antagonist of TRPV1 receptor with IC50 of 562 nM. It is synthetic analogue of sensory neurone excitotoxin. |
| FB09172 |
Capsaicin
|
404-86-4 |
Capsaicin is an agonist of TRPV1 with EC50 of 0.29 ± 0.05 μM in HEK293 cells. It is active component of chili peppers. |
| FB05920 |
6-Gingerol
|
23513-14-6 |
6-Gingerol is activator transient receptor potential vanilloid receptor TRPV1 and TRP ankyrin receptor TRPA1 with EC50 of 3.3 µM and 10.4 µM. It's a natural chemical found in the rhizomes of ginger (Z. officinale). |