Coumarins
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| FB04299 | Wedelolactone | 524-12-9 | Wedelolactone, a natural compound derived from Chinese herbal medicine Eclipta prostrate L, is an anti-cancer agent for breast and prostate carcinomas in vitro and in vivo targeting multiple cellular proteins including androgen receptors, 5-lipoxygenase and topoisomerase IIα. |
| FB04530 | Tomentin | 28449-62-9 | Tomentin, a natural product isolated and purified from the barks of Jatropha curcas, can inhibit papain-like protease and has anti-inflammatory activity. |
| FB04186 | Suberosin | 581-31-7 | Suberosin, a natural product isolated and purified from the roots of Angelica pubescens, inhibits PHA-induced PBMC proliferation, at least in part, through reduction of [Ca2+]i, ERK, NF-AT, and NF-kappaB activation, and early gene expression in PBMC including cyclins and cytokines, and arrest of cell cycle progression in the cells. |
| FB04269 | Sphondin | 483-66-9 | Sphondin, a natural product isolated and purified from the fruits of Heracleum sibiricum L., possesses an inhibitory effect on IL-1beta-induced increase in the level of COX-2 protein and PGE(2) release in A549 cells. |
| FB04536 | Selinidin | 19427-82-8 | Selinidin, a natural product isolated and purified from the herbs of Peucedanum harry-smithii var. subglabrum, decreases phosphorylation of phospholipase C-gamma1, p38 mitogen-activated protein kinase, and IkappaB-alpha upon FcepsilonRI stimulation. |
| FB03656 | Scopoletin Acetate | 56795-51-8 | Scopoletin acetate is a natural product isolated and purified from the herbs of Atropa belladonna L.. |
| FB04302 | Samidin | 477-33-8 | Samidin, a natural product isolated and purified from the fruits of Ammi visnaga., has anti-inflammatory properties through suppression of NF-κB and AP-1-mediated-genes in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. |
| FB04534 | Rutaretin | 13895-92-6 | Rutaretin is a natural product isolated and purified from the herbs of Ruta graveolens L.. |
| FB04297 | Phebalosin | 6545-99-9 | Phebalosin, a natural product isolated and purified from the herbs of Murraya exotica L., displays EC(50) of 14.1 mg/mL against axenic amastigote forms of Leishmania panamensis. and cytotoxicity (IC(50)) at concentrations of 20.7 mg/mL on human promonocytic U-937 cells. |
| FB04538 | Peucedanol | 20516-23-8 | Peucedanol is a natural product isolated and purified from Formosan Peucedanum japonicum. |
| FB04303 | Oxypeucedanin Hydrate | 133164-11-1 | Oxypeucedanin is a chemical constituent from polarity part in roots of Angelica dahurica var. formosana cv. Chuanbaizhi. |
| FB04306 | Osthol Hydrate | 69219-24-5 | Osthol is a natural product isolated and purified from the fructus of Cnidium monnieri (L.) Cusson. |
| FB08765 | Notopterol | 88206-46-6 | Notopterol induces apoptosis and inhibits cell cycle-specific, it's a natural product isolated and purified from the roots of Notopterygium incisum. |
| FB04381 | Nodakenetin | 495-32-9 | Nodakenetin is a natural product isolated and purified from the herbs of Peucedanum decursivum Maxim. with clinical efficacy. |
| FB04540 | Neoglycyrol | 23013-84-5 | Neoglycyrol is a natural product isolated and purified from the roots of Glycyrrhiza uralensis Fisch with some cardioprotective effects . |
| FB04526 | Murraxocin | 88478-44-8 | Murraxocin is a natural insecticidal coumarin isolated and purified from the herbs of Murraya exotica L. |
| FB04523 | Murrangatin | 37126-91-3 | Murrangatin, a natural anti-tumor-promoting agent isolated and purified from the herbs of Murraya exotica L., exhibits cytotoxicity against cholangiocarcinoma cell line and significantly inhibits EBV-EA activation, and preserves the high viability of Raji cells. |
| FB04527 | Murrangatin Diacetate | 51650-59-0 | Murrangatin diacetate is a natural product isolated and purified from the rootbarks of Morus alba. |
| FB04380 | mMelin | 15085-71-9 | mMelin is a natural product isolated and purified from the herbs of Micromelum integerrimum with antitumor activity and cytotoxicity against cholangiocarcinoma cell line, KKU-100. |
| FB04525 | Minumicrolin | 88546-96-7 | Minumicrolin, a natural potential anti-tumor agent isolated and purified from the herbs of Murraya exotica L., shows mild butyrylcholinesterase inhibition activity and exhibits cytotoxicity against cholangiocarcinoma cell line, KKU-100. |
| FB04290 | Meranzin Hydrate | 5875-49-0 | Meranzin, a natural product isolated and purified from the roots of Angelica biserrata, produces a rapid effect mediated by AMPA receptors and involving BDNF modulation through the ERK1/2 pathway. Meranzin can also induce similar effect to Fructus Aurantii on intestinal motility and it was, at least in part, mediated by stimulation of H1 histamine receptors, and exhibits antidepressive and prokinetic-like effects through the regulation of the common mediator, the alpha 2-adrenoceptor , and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors. |
| FB04298 | Meranzin | 23971-42-8 | Meranzin, a natural product isolated and purified from the peel of Citrus maxima, can induce similar effect to Fructus Aurantii on intestinal motility and it was, at least in part, mediated by stimulation of H1 histamine receptors. |
| FB04255 | Mellein | 480-33-1 | Mellein is a natural product isolated and purified from the herbs of Goniothalamus griffithii. |
| FB04537 | Khellactone | 24144-61-4 | Khellactone, a natural product isolated and purified from the roots of Angelica purpuraefolia with antitumor and antiplasmodial activities. It can suppress the growth of NCI-H460 tumor cells. |
| FB04532 | Isomeranzin | 1088-17-1 | Isomeranzin is a natural product isolated and purified from the peels of Citrus maxima with antimycobacterial activity. |
| FB04539 | Hyuganin D | 77331-76-1 | Hyuganin D is a natural product isolated and purified from the roots of Angelica furcijuga Kitagawa. |
| FB04254 | Heraclenol | 31575-93-6 | Heraclenol, a natural product isolated and purified from the herbs of Heracleum repula Franch, can inhibit the proliferation of melanoma cells and cell cycle. |
| FB04529 | Heraclenol 3'-O-beta-D-Glucopyranoside | 32207-10-6 | Heraclenol 3'-O-beta-D-glucopyranoside is a natural product isolated and purified from the herbs of Heracleum repula Franch.. |
| FB04528 | Hainanmurpanin | 95360-22-8 | Hainanmurpanin is a natural product isolated and purified from the herbs of Murraya exotica L.. |
| FB04541 | Glycyrin | 66056-18-6 | Glycyrin, a natural potential MRP inhibitor isolated and purified from the roots of Glycyrrhiza uralensis Fisch, shows inhibitory effects on copper-induced protein oxidative modification of mice brain homogenate in vitro. |
| FB04542 | Glycycoumarin | 94805-82-0 | Glycycoumarin, a natural product isolated and purified from Glycyrrhizae Radix, inhibits hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress/GSK-3-mediated mitochondrial pathway. |
| FB04305 | Erythrocentaurin | 50276-98-7 | Erythrocentaurin is a hepatitis B virus inhibitor. |
| FB04383 | Erythrocentauric Acid | 90921-13-4 | Erythrocentauric acid is a natural product isolated and purified from the root of Gentiana macrophylla. |
| FB09037 | Demethylwedelolactone | 6468-55-9 | Demethylwedelolactone, a natural product isolated and purified from the herbs of Eclipta prostrata, has trypsin inhibitory effect. Demethylwedelolactone exerts anti-invasive growth effect on breast cancer cells. |
| FB04535 | Demethylsuberosin | 21422-04-8 | Demethylsuberosin, a natural product isolated and purified from the root of Angelica dahuricae, displays suppressive effects on LPS-induced NO and PGE2 production with the IC50 value of 9.42 uM, suggesting that it has potential anti-inflammatory activity. |
| FB04524 | Coumurrayin | 17245-25-9 | Coumurrayin is a natural product isolated and purified from the herbs of Murraya paniculata (L.) Jack. |
| FB06755 | Chloculol | 131652-35-2 | Chloculol is a natural product. |
| FB04531 | Calycanthoside | 483-91-0 | Calycanthoside has the anti-inflammatory effect, it has inhibitory activity on NO production. Isofraxidin 7-O-β-D-Glucoside shows antibacterial activity. |
| FB04543 | Apterin | 53947-89-0 | Apterin is a natural product isolated and purified from the herbs of Peucedanum decursivum Maxim. with anti-inflammatory activity in vitro. It shows significantly inhibitory activity on nitric oxide production in RAW264.7 cells. |
| FB03784 | 7-Hydroxy-3-Prenylcoumarin | 86654-26-4 | 7-Hydroxy-3-prenylcoumarin is a natural product isolated and purified from the herbs of Coriaria nepalensis. |
| FB03612 | 7-Geranyloxy-6-Methoxycoumarin | 28587-43-1 | 7-Geranyloxy-6-methoxycoumarin is a natural product isolated and purified from the herbs of Murraya tetramera Huang, showing significant cytotoxicity against three cell lines (A549, SMMC-7721 and BALL-1). |
| FB03668 | 5,7,8-Trimethoxycoumarin | 60796-65-8 | 5,7,8-Trimethoxycoumarin is a natural product isolated and purified from the herbs of Viola yedonensis Makino. |
| FB03655 | 5,6,7,8-Tetramethoxycoumarin | 56317-15-8 | 5,6,7,8-Tetramethoxycoumarin is a natural product isolated and purified from the herbs of Croton laevigatus. |
| FB06758 | 2-(1-Hydroxy-1-Methylethyl)-4-Methoxy-7H-Furo[3,2-G][1]benzopyran-7-One | 54087-32-0 | 2-(1-Hydroxy-1-methylethyl)-4-methoxy-7H-furo[3,2-g][1]benzopyran-7-one is a natural product isolated and purified from the fruits of Evodia lepta. |
| FB04332 | (-)-Praeruptorin B | 4970-26-7 | (-)-Praeruptorin B is a natural product isolated and purified from Peucedani Radix. |
| FB04301 | (-)-Praeruptorin A | 14017-71-1 | (-)-Praeruptorin A, a natural product isolated and purified from the herbal medicine Peucedanum praeruptorum, inhibits in vitro migration of preosteoclasts and in vivo bone erosion, possibly due to its potential to target calmodulin. |
| FB04304 | (-)-Heraclenol | 139079-42-8 | (-)-Heraclenol is a natural product isolated and purified from the roots of Angelica dahurica var. formosana cv. Chuanbaizhi. |
| FB04333 | (+)-Pteryxin | 13161-75-6 | (+)-Pteryxin, a natural product isolated and purified from the herbs of Peucedanum harry-smithii var. subglabrum, has muscle-relaxant property and shows hepatoprotective and nitric oxide prodn. inhibitory activity. |
| FB10550 | (+)-Praeruptorin A | 73069-27-9 | (+)-Praeruptorin A is a natural product isolated and purified from the roots of Peucedanum praeruptorum Dunn., which exerted distinct relaxant effects on isolated rat aorta rings, which might be mainly attributed to nitric oxide synthesis catalyzed by endothelial nitric oxide synthase. |
| FB04270 | (+)-Mellein | 62623-84-1 | (+)-Mellein is a natural product isolated and purified from the herbs of Goniothalamus griffithii. |