VU0134992 hydrochloride 2-(2-溴-4-异丙基苯氧基)-N-(2,2,6,6-四甲基哌啶-4-基)乙酰胺盐酸盐 Cat No. FB17927Cas No. 1052515-91-9
VU0134992 hydrochloride is the first subtype-preferring, orally active and selective Kir4.1 potassium channel pore blocker, with an IC50 of 0.97 µM. VU0134992 hydrochloride is 9-fold selective for homomeric Kir4.1 over Kir4.1/5.1 concatemeric channels (IC50=9 µM) at -120 mV.
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18817579266
18817579266