TRPM8 antagonist 14 (S)-2-(二苄氨基)-3-(1H-吲哚-3-基)丙酸甲酯 Cat No. FB17562Cas No. 259674-19-6
TRPM8 antagonist 14 is a tryptophan-derived selective TRPM8 antagonist with IC50 value of 0.2nM. It showed significant target coverage in both an icilin-induced WDS (at 1-30 mg/kg s.c.) and oxaliplatin-induced cold allodynia (at 0.1-1 μg s.c.) mice models.
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18817579266
18817579266