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ASK1 Inhibitor 10 is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1). It is selective for ASK1 over ASK2 as well as MEKK1, TAK-1, IKKβ, ERK1, JNK1, p38α, GSK3β, PKCθ, and B-RAF. It inhibits streptozotocin-induced increases in JNK and p38 phosphorylation in INS-1 pancreatic β cells in a concentration-dependent manner.
规格 | 价格 | 促销价格 | 库存 |
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18817579266
实验数据
技术信息
CAS号 | 1005775-56-3 | 储存条件 |
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分子式 | C21H23Cl2N5O | 运输 | 蓝冰 | |
分子量 | 432.35 | 别名 |
生物活性