CAS:83-48-7Stigmasterol

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Stigmasterol is among the most abundant of plant sterols used as a food additive, with potential effect on lowering the levels of LDL cholesterol.

规格	价格	促销价格	库存

18817579266

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18817579266

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实验数据

技术信息

CAS号

83-48-7

储存条件

分子式

C29H48O

运输

蓝冰

分子量

412.69

别名

溶解度

动物实验配方

生物活性

描述Stigmasterol, a natural compound isolated from Azadirachta indica, has many biological activities. In vitro studies, stigmasterol could induce apoptosis in hepatocarcimona (HepG2) cells by regulating the expression of some special genes. Besides this, it was found that stigmasterol could inhibit the activity of a partially purified bloodstream T. congolense sialidase with an inhibition binding constant of 356.59 μM. In vivo studies, stigmasterol could contribute to the improvement of skin tumors induced by 7,12-dimethylbenz[a]anthracene in swiss albino mice, possibly because of its oxidative stress response. In addition, stigmasterol has the ability of relieving some special skin inflammatory features in rodents.
动物研究
剂量
Rat: 20 mg/kg - 80 mg/kg^[5] (i.p.); 10 mg/kg - 300 mg/kg^[6] (p.o.) Mice: 10 mg/kg - 100 mg/kg^[7] (i.p.); 50 mg/kg - 200 mg/kg^[7] (p.o.)

给药途径
i.p., p.o.

动物研究
剂量	Rat: 20 mg/kg - 80 mg/kg^[5] (i.p.); 10 mg/kg - 300 mg/kg^[6] (p.o.) Mice: 10 mg/kg - 100 mg/kg^[7] (i.p.); 50 mg/kg - 200 mg/kg^[7] (p.o.)
给药途径	i.p., p.o.