CAS:98-97-5Pyrazine-2-carboxylic acid

您的位置 : 首页 / Metabolic Enzyme / Dehydrogenase / Pyrazinecarboxylic acid

Pyrazinecarboxylic acid 2-甲酸吡嗪 Cat No. FB15624Cas No. 98-97-5

Synonyms: Pyrazine-2-carboxylic acid;PCA;pyrazine‐2‐carboxylic acid; pyrazinoic acid; pyrazoic acid; pyrazinic acid; paradiazinecarboxylic acid; 2‐carboxypyrazine.

Pyrazinoic Acid inhibits Mycobacterial Coenzyme A biosynthesis by binding to aspartate decarboxylase PanD.

规格	价格	促销价格	库存

18817579266

立即询价

咨询

18817579266

立即询价

实验数据

储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 8.0582 mL
- 40.2909 mL
- 80.5818 mL
- 5 mM
- 1.6116 mL
- 8.0582 mL
- 16.1164 mL
- 10 mM
- 0.8058 mL
- 4.0291 mL
- 8.0582 mL
计算器摩尔计算器总药量计算器工作液计算器

技术信息

CAS号	98-97-5	储存条件	粉末 -20°C 3 年液体 -80°C 12 月
分子式	C5H4N2O2	运输	蓝冰
分子量	124.10	别名	Pyrazine-2-carboxylic acid;PCA;pyrazine‐2‐carboxylic acid; pyrazinoic acid; pyrazoic acid; pyrazinic acid; paradiazinecarboxylic acid; 2‐carboxypyrazine.

靶点数据

生物活性

描述Pyrazinecarboxylic acid is an active metabolite of pyrazinamide. Pyrazinamidean is an anti-tubercular agent. In this model for the evaluation of the effects of uricosuric agents, the urinary excretion of pyrazinecarboxylic acid was decreased by probenecid and indicated an inverse correlation between urinary excretion of urate and pyrazinecarboxylic acid. In the in vitro study, the treatment of the vesicles of rat renal brush-border membrane with pyrazinecarboxylic acid produced an increased urate uptake, which was inhibited by uricosuric agents^[2]. PZA (pyrazinamide) is converted to pyrazinecarboxylic acid (POA) in plant cells, suppressing the activity of 1-aminocyclopropane-1-carboxylic acid oxidase (ACO), the enzyme catalysing the final step of ethylene formation^[3].