CAS:1566586-52-4Pseudouridimycin

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Pseudouridimycin Cat No. FB11100Cas No. 1566586-52-4

Synonyms: PUM

Pseudouridimycin is a natural product that potently and selectively inhibits bacterial RNAP in vitro, inhibits bacterial growth in culture, and clears infection in a mouse model of Streptococcus pyogenes peritonitis.

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18817579266

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18817579266

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实验数据

储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.0558 mL
- 10.2788 mL
- 20.5575 mL
- 5 mM
- 0.4112 mL
- 2.0558 mL
- 4.1115 mL
- 10 mM
- 0.2056 mL
- 1.0279 mL
- 2.0558 mL
计算器摩尔计算器总药量计算器工作液计算器

技术信息

CAS号	1566586-52-4	储存条件	粉末 -20°C 3 年液体 -80°C 12 月
分子式	C17H26N8O9	运输	蓝冰
分子量	486.44	别名	PUM

靶点数据

生物活性

描述Pseudouridimycin is a natural product that potently and selectively inhibits bacterial RNAP in vitro, inhibits bacterial growth in culture, and clears infection in a mouse model of Streptococcus pyogenes peritonitis. PUM inhibits RNAP through a binding site on RNAP (the NTP addition site) and mechanism (competition with UTP for occupancy of the NTP addition site) that differ from those of the RNAP inhibitor and current antibacterial drug rifampin (Rif).