CAS:479-92-5Propyphenazone

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Propyphenazone Cat No. FB03039Cas No. 479-92-5

Synonyms: Isopropylantipyrine;Isopropyrine

Propyphenazone is a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, Propyphenazone-based analogues as prodrugs and selective cyclooxygenase-2 inhibitors.

规格	价格	促销价格	库存

18817579266

立即询价

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18817579266

立即询价

实验数据

储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 4.3421 mL
- 21.7103 mL
- 43.4206 mL
- 5 mM
- 0.8684 mL
- 4.3421 mL
- 8.6841 mL
- 10 mM
- 0.4342 mL
- 2.1710 mL
- 4.3421 mL
计算器摩尔计算器总药量计算器工作液计算器

技术信息

CAS号

479-92-5

储存条件

粉末: -20°C 3 年

液体: -80°C 12 月

分子式

C14H18N2O

运输

蓝冰

分子量

230.31

别名

Isopropylantipyrine;Isopropyrine

溶解度

DMSO	46.0 mg/mL (199.7 mM)

动物实验配方

靶点数据

生物活性

描述Propyphenazone is a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, Propyphenazone-based analogues as prodrugs and selective cyclooxygenase-2 inhibitors^[3]. Prenatal coadministration of propyphenazone with caffeine or paracetamol caused intrauterine growth retardation but did not increase external or internal or paracetamol caused intrauterine growth retardation but did not increase external or internal congenital anomalies^[4]. On a per milligram basis, the relative analgesic potency of propyphenazone was about twice that of ASA (acetylsalicylic acid)^[5]. Propyphenazone 220 mg was administered orally to volunteers. Maximum plasma concentrations between 1.5 microgram/ml and 3.5 micrograms/ml were found 30 min later. After comparable doses plasma concentrations in dog and rabbit were lower^[6].