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Pemigatinib  3-(2,6-二氟-3,5-二甲氧基苯基)-1-乙基-8-(吗啉代甲基)-1,3,4,6-四氢-2H-吡咯并[3',2':5,6]吡啶并[4,3-d]嘧啶-2-酮 Cat No. FB17296Cas No. 1513857-77-6

Synonyms: INCB054828

Pemigatinib, also known as INCB054828, is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) types 1, 2, and 3 (FGFR1/2/3), with potential antineoplastic activity. FGFR inhibitor INCB054828 binds to and inhibits FGFR1/2/3, which may result in the inhibition of FGFR1/2/3-related signal transduction pathways. This inhibits proliferation in FGFR1/2/3-overexpressing tumor cells.

规格 价格 促销价格 库存

18817579266

18817579266

文件信息: 批次信息

实验数据

技术信息

CAS号 1513857-77-6 储存条件
分子式 C24H27F2N5O4 运输 蓝冰
分子量 487.50 别名 INCB054828
溶解度
DMSO40.0 mg/mL (82.1 mM)
WaterInsoluble
EthanolInsoluble
动物实验配方

靶点数据

生物活性

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