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ONO-7475 is a potent and selective inhibitor of active novel Axl/Mer tyrosine kinase with IC50 values of 0.7nM and 1nM, respectively. It potently arrested growth and induced apoptosis in acute myeloid leukemia with internal tandem duplication mutation of FMS-like tyrosine kinase 3.
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18817579266
实验数据
技术信息
CAS号 | 1646839-59-9 | 储存条件 |
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分子式 | C32H26N4O6 | 运输 | 蓝冰 | |||||||
分子量 | 562.57 | 别名 | ||||||||
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动物实验配方 |
生物活性