CAS:1448867-41-1NVP-HDM 201

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NVP-HDM 201 Cat No. FB11061Cas No. 1448867-41-1

Synonyms: NVP-HDM201

HDM201 binds to the p53 binding-site of the Mdm2 protein, disrupting the interaction of the two proteins and leading to the activation of the p53 pathway. It induces robust p53-dependent cell cycle arrest and apoptosis in human p53 wild-type tumor cells. HDM201 exhibits highly selectivity across a panel of cancer cell lines.

规格	价格	促销价格	库存

18817579266

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18817579266

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实验数据

储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 1.8005 mL
- 9.0023 mL
- 18.0046 mL
- 5 mM
- 0.3601 mL
- 1.8005 mL
- 3.6009 mL
- 10 mM
- 0.1800 mL
- 0.9002 mL
- 1.8005 mL
计算器摩尔计算器总药量计算器工作液计算器

技术信息

CAS号

1448867-41-1

储存条件

粉末: -20°C 3 年

液体: -80°C 12 月

分子式

C26H24Cl2N6O4

运输

蓝冰

分子量

555.41

别名

NVP-HDM201

溶解度

DMSO	37.5 mg/mL (67.5 mM)
Water	insoluble

动物实验配方

靶点数据

生物活性

描述HDM201 binds to the p53 binding-site of the Mdm2 protein, disrupting the interaction of the two proteins and leading to the activation of the p53 pathway. It induces robust p53-dependent cell cycle arrest and apoptosis in human p53 wild-type tumor cells. HDM201 exhibits highly selectivity across a panel of cancer cell lines.