CAS:6385-02-0Meclofenamate Sodium

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Meclofenamate Sodium 甲氯灭酸钠 Cat No. FB03904Cas No. 6385-02-0

Meclofenamate Sodium is a dual COX-1/COX-2 inhibitor with IC50 of 40 nM and 50 nM, respectively, used in the treatment of joint, muscular pain, arthritis and dysmenorrhea.

规格	价格	促销价格	库存

18817579266

立即询价

咨询

18817579266

立即询价

实验数据

储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 3.1434 mL
- 15.7168 mL
- 31.4336 mL
- 5 mM
- 0.6287 mL
- 3.1434 mL
- 6.2867 mL
- 10 mM
- 0.3143 mL
- 1.5717 mL
- 3.1434 mL
计算器摩尔计算器总药量计算器工作液计算器

技术信息

CAS号

6385-02-0

储存条件

粉末: -20°C 3 年

液体: -80°C 12 月

分子式

C14H10Cl2NNaO2

运输

蓝冰

分子量

318.13

别名

溶解度

DMSO	62.0 mg/mL (194.9 mM)
Water	61.0 mg/mL (191.7 mM)
Ethanol	60.0 mg/mL (188.6 mM)

动物实验配方

靶点数据

生物活性

描述Meclofenamate Sodium (MS) is an nonsteroidal anti-inflammatory drugs (NSAIDs) used to reduce pain. Addition of exogenous proteasome to MS treated cells improved cell viability^[2]. Single 100- and 200-mg doses of meclofenamate sodium are as safe as, and significantly more effective than, codeine 60 mg or placebo for episiotomy pain^[3]. In the majority of patients (headache and craniofacial pain), the meclofenamate sodium period scored lowest or second-lowest after the follow-up period in mean pain intensity^[4]. Meclofenamate sodium in the dose administered was equally effective in relieving pain and inflammation and restoring restricted function in patients with acute gout as indometacin when used in the generally recommended dose for this indication. Meclofenamate sodium, even at these high dosage levels, was better tolerated than indometacin^[5]. Similar improvement in mobility of the vertebral column and spondylitic pain could be achieved with meclofenamate sodium and indometacin in patients with ankylosing spondylitis. Meclofenamate sodium offers an effective and safe alternative to indometacin in the treatment of patients with ankylosing spondylitis^[6].