CAS:70374-39-9Lornoxicam

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Lornoxicam 氯诺昔康 Cat No. FB03560Cas No. 70374-39-9

Synonyms: Chlortenoxicam;Ro139297;TS-110

Lornoxicam is a COX inhibitor with IC50 of 5 nM and 8 nM for COX1 and 2 respectively. It's a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of various types of pain.

规格	价格	促销价格	库存

18817579266

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18817579266

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实验数据

储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.6895 mL
- 13.4474 mL
- 26.8947 mL
- 5 mM
- 0.5379 mL
- 2.6895 mL
- 5.3789 mL
- 10 mM
- 0.2689 mL
- 1.3447 mL
- 2.6895 mL
计算器摩尔计算器总药量计算器工作液计算器

技术信息

CAS号

70374-39-9

储存条件

粉末: -20°C 3 年

液体: -80°C 12 月

分子式

C13H10ClN3O4S2

运输

蓝冰

分子量

371.82

别名

Chlortenoxicam;Ro139297;TS-110

溶解度

DMSO	3.0 mg/mL (8.1 mM) warming
Water	Insoluble
Ethanol	Insoluble

动物实验配方

靶点数据

生物活性

描述Lornoxicam is a strong analgesic and anti-inflammatory NSAID with balanced cyclo-oxygenase (COX-1/COX-2) inhibition and excellent tolerability. Lornoxicam and rofecoxib are effective in the treatment of patients with activated osteoarthritis; the analgesic and anti-inflammatory effects of lornoxicam are significantly superior to those of rofecoxib without inferiority in tolerability^[3]. The developed proniosomal gel (F19) improved the clinical efficacy of lornoxicam as compared to oral therapy. Graphical Abstract Proniosomal gel for transdermal delivery of lornoxicam: optimization using factorial design and in vivo evaluation in rats^[4]. Lornoxicam was also as effective as other NSAIDs in relieving symptoms of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute sciatica and low back pain^[5].