CAS:42461-84-7Flunixin meglumine

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Flunixin meglumine is a potent inhibitor of COX used as analgesic agent with anti-inflammatory and antipyretic activity.

规格	价格	促销价格	库存

18817579266

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18817579266

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实验数据

技术信息

CAS号

42461-84-7

储存条件

分子式

C21H28F3N3O7

运输

蓝冰

分子量

491.46

别名

溶解度

动物实验配方

生物活性

描述Flunixin Meglumine (FM) is a potent inhibitor of COX used as analgesic agent with anti-inflammatory and antipyretic activity. Intravenous FM, 1.1 mg kg-1, significantly inhibited carrageenan-induced exudate PGE2 formation (Emax, 100%, IC50, < 0.4 nM) and serum TXB2 generation (Emax, 100%, IC50, 17 nM) for up to 32 h. Flunixin meglumine significantly inhibited the rise in skin temperature but had a limited effect on exudate WBC(white blood cell). Flunixin meglumine was a more potent COX inhibitor than PBZ (phenylbutazone) and was more selective for the inducible form of COX in vivo^[3]. Administration of flunixin meglumine improved pregnancy rates in excitable recipient cows following embryo transfer without affecting the proportion of non-pregnant cows returning to estrus^[4].