CAS:70553-76-3Daurisoline

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Daurisoline Cat No. FB06629Cas No. 70553-76-3

Daurisoline, a natural product isolated and purified from the roots of Menispermum dauricu with antiarrhythmic effects, exerts a blocking effect on hERG at concentrations below 30 uM, but does not affect the expression and function of the hERG channel.

规格	价格	促销价格	库存

18817579266

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18817579266

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实验数据

储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 1.6374 mL
- 8.1868 mL
- 16.3736 mL
- 5 mM
- 0.3275 mL
- 1.6374 mL
- 3.2747 mL
- 10 mM
- 0.1637 mL
- 0.8187 mL
- 1.6374 mL
计算器摩尔计算器总药量计算器工作液计算器

技术信息

CAS号	70553-76-3	储存条件	粉末 -20°C 3 年液体 -80°C 12 月
分子式	C37H42N2O6	运输	蓝冰
分子量	610.74	别名

靶点数据

生物活性

描述Daurisoline, a natural product isolated and purified from the roots of Menispermum dauricu with antiarrhythmic effects, exerts a blocking effect on hERG at concentrations below 30 uM, but does not affect the expression and function of the hERG channel. Daurisoline can inhibit early afterdepolarizations (EADs) which may be associated with its blockade effects on I(Ca-L), shows cytoprotective effects on ischemic injury in cultured pheochromocytoma (PC12) cells, which are mediated by blocking Ca2+ influx into cells, and inhibits the delayed afterdepolarization and triggered activity by preventing an increase of alpha Cai via transmembrane Ca2+ entry and Ca2+ release from the reticulum.