CAS:5870-29-12-(Dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate hydrochloride

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Cyclopentolate HCl 盐酸环喷托酯 Cat No. FB16611Cas No. 5870-29-1

Synonyms: DL-Cyclopentolate hydrochloride

Cyclopentolate (DL-Cyclopentolate) hydrochloride is an Atropine-like muscarinic receptors antagonist with a pKB value of 7.8 (on the circular ciliary muscle). Cyclopentolate hydrochloride is an anti-muscarinic agent commonly used in the ophthalmologic practice.

规格	价格	促销价格	库存

18817579266

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18817579266

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实验数据

储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 3.0502 mL
- 15.2511 mL
- 30.5021 mL
- 5 mM
- 0.6100 mL
- 3.0502 mL
- 6.1004 mL
- 10 mM
- 0.3050 mL
- 1.5251 mL
- 3.0502 mL
计算器摩尔计算器总药量计算器工作液计算器

技术信息

CAS号

5870-29-1

储存条件

粉末: -20°C 3 年

液体: -80°C 12 月

分子式

C17H26ClNO3

运输

蓝冰

分子量

327.85

别名

DL-Cyclopentolate hydrochloride

溶解度

DMSO	66.0 mg/mL (201.3 mM)
Ethanol	66.0 mg/mL (201.3 mM)

动物实验配方

靶点数据

生物活性

描述Cyclopentolate HCl is an anti-muscarinic agent commonly used in the ophthalmologic practice. The pKB values of muscarinic antagonists on the circular ciliary muscle was cyclopentolate, 7.8^[4]. Mydriasis by cyclopentolate may complicate ChT measurements by EDI OCT (enhanced depth imaging (EDI) optical coherence tomography)^[5]. Placing one drop of cyclopentolate HCL 1% on a closed eyelid had a success rate for complete cycloplegia that was equivalent to placing one drop directly on the cornea^[6]. Combining cyclopentolate base to polygalacturonic (CY-PGA) or hyaluronic (CY-HA) acid resulted in an increased mydriatic effect when compared with cyclopentolate hydrochloride (CY-HCl). The ocular penetration of cyclopentolate, based on drug concentrations in aqueous humor 30 minutes after the eyedrop instillation, was increased 3 fold when the polygalacturonate complex was used^[7].