CAS:2101314-20-7CX-5461 HCl

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CX-5461 HCl Cat No. FB11363Cas No. 2101314-20-7

CX-5461 HCl is a potent and orally bioavailable inhibitor of Pol I-mediated rRNA synthesis, with IC50s of 142 nM in HCT-116, 113 nM in A375, and 54 nM in MIA PaCa-2 cells, and shows little or no effect on Pol II (IC50 ≥25 μM).

规格	价格	促销价格	库存

18817579266

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18817579266

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实验数据

储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 1.8179 mL
- 9.0897 mL
- 18.1793 mL
- 5 mM
- 0.3636 mL
- 1.8179 mL
- 3.6359 mL
- 10 mM
- 0.1818 mL
- 0.9090 mL
- 1.8179 mL
计算器摩尔计算器总药量计算器工作液计算器

技术信息

CAS号	2101314-20-7	储存条件	粉末 -20°C 3 年液体 -80°C 12 月
分子式	C27H28ClN7O2S	运输	蓝冰
分子量	550.08	别名

靶点数据

生物活性

描述CX-5461 HCl is a potent and orally bioavailable inhibitor of Pol I-mediated rRNA synthesis, with IC50s of 142 nM in HCT-116, 113 nM in A375, and 54 nM in MIA PaCa-2 cells, and shows little or no effect on Pol II (IC50 ≥25 μM).