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CD80-IN-3 binds with high specificity and low nanomolar affinity to CD80. It has relatively slow off-rates, blocks both CD28 and CTLA-4 binding and inhibits proinflammatory cytokine release in T cell assays with submicromolar potency.
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18817579266
实验数据
技术信息
CAS号 | 486449-65-4 | 储存条件 |
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分子式 | C17H10FN3O3 | 运输 | 蓝冰 | |||
分子量 | 323.28 | 别名 | ||||
溶解度 |
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动物实验配方 |
生物活性