CAS:1197996-80-7CBL-0137

您的位置 : 首页 / Cell Cycle / DNA/RNA Synthesis / CBL0137

CBL0137 Cat No. FB06659Cas No. 1197996-80-7

Synonyms: CBLC137;Curaxin-137

CBL-0137 is a metabolically stable curaxin that activates p53 with an EC50 value of 0.37 µM and inhibits NF-κB with an EC50 of 0.47 µM. It functionally inactivates the facilitates chromatin transcription complex (FACT), driving the effects on p53 and NF-κB and promoting cancer cell death.

规格	价格	促销价格	库存

18817579266

立即询价

咨询

18817579266

立即询价

实验数据

储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.9724 mL
- 14.8620 mL
- 29.7241 mL
- 5 mM
- 0.5945 mL
- 2.9724 mL
- 5.9448 mL
- 10 mM
- 0.2972 mL
- 1.4862 mL
- 2.9724 mL
计算器摩尔计算器总药量计算器工作液计算器

技术信息

CAS号	1197996-80-7	储存条件	粉末 -20°C 3 年液体 -80°C 12 月
分子式	C21H24N2O2	运输	蓝冰
分子量	336.43	别名	CBLC137;Curaxin-137

靶点数据

生物活性

描述CBL-0137 is a metabolically stable curaxin that activates p53 with an EC50 value of 0.37 µM and inhibits NF-κB with an EC50 of 0.47 µM. It functionally inactivates the facilitates chromatin transcription complex (FACT), driving the effects on p53 and NF-κB and promoting cancer cell death.
动物研究
剂量
Mice: 25 mg/kg^[3] (p.o.); 90 mg/kg^[3] (i.p.); 50 mg/kg^[4] (i.v.)

给药途径
p.o., i.p., i.v.

动物研究
剂量	Mice: 25 mg/kg^[3] (p.o.); 90 mg/kg^[3] (i.p.); 50 mg/kg^[4] (i.v.)
给药途径	p.o., i.p., i.v.