CAY10404 3-(4-(甲基磺酰基)苯基)-4-苯基-5-(三氟甲基)异恶唑 Cat No. FB17694Cas No. 340267-36-9
CAY10404 is a potent and highly selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 1 nM. CAY10404 exhibits no inhibition of COX-1 (IC50>500 µM) . CAY10404 is a potent inhibitor of PKB/Akt and MAPK signalling pathways and induces apoptosis in NSCLC cells. CAY10404, a diarylisoxazole, has good analgesic, anti-inflammatory, and anti-cancer activities .
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18817579266
18817579266