CAS:5234-68-4Carboxin

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Carboxin is an fungicide used in agriculture.

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18817579266

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18817579266

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实验数据

技术信息

CAS号

5234-68-4

储存条件

分子式

C12H13NO2S

运输

蓝冰

分子量

235.30

别名

溶解度

DMSO	47.0 mg/mL (199.7 mM)

动物实验配方

生物活性

描述Carboxin (Carboxine) is a systemic agricultural fungicide and seed protectant. Carboxin demonstrates high specificity against the fungal class Basideomycetes, Deuteromycetes and Phycomycetes^[1]. Carboxin is a potent inhibitor of the enzyme of certain organisms. The bacterium Paracoccus denitrificans was found to be sensitive to carboxin in vivo, and mutants that grow in the presence of 3'-methyl carboxin were isolated^[2]. The systemic fungicide carboxin (5,6-dihydro-2-methyl-1,4-oxathiin-3-carboxanilide) inhibited oxidation of succinate by membranes prepared from Micrococcus denitrificans, the K(i) being 16 muM. Carboxin also inhibited dichlorophenol indophenol (DCIP) reductase activities in a manner both qualitatively and quantitatively similar to the inhibition of oxidation of the various substrates^[3].