CAS:195615-84-01-(2,2-Diphenyltetrahydrofuran-3-yl)-N,N-dimethylmethanamine hydrochloride

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Anavex 2-73 HCl Cat No. FB09897Cas No. 195615-84-0

Synonyms: AVex-73 HCl

σ1 agonist (IC50 = 860 nM); also displays affinity for muscarinic M1-M4 receptors (Ki values < 500 nM), but not for σ2 receptors. Exhibits neuroprotective effects, prevents tau hyperphosphorylation, and attenuates scopolamine- and (+)-MK 801-induced learning deficits in a mouse model of amyloid toxicity.

规格	价格	促销价格	库存

18817579266

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18817579266

立即询价

实验数据

储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 3.1461 mL
- 15.7307 mL
- 31.4614 mL
- 5 mM
- 0.6292 mL
- 3.1461 mL
- 6.2923 mL
- 10 mM
- 0.3146 mL
- 1.5731 mL
- 3.1461 mL
计算器摩尔计算器总药量计算器工作液计算器

技术信息

CAS号

195615-84-0

储存条件

粉末: -20°C 3 年

液体: -80°C 12 月

分子式

C19H24ClNO

运输

蓝冰

分子量

317.85

别名

AVex-73 HCl

溶解度

DMSO	64.0 mg/mL (201.4 mM)
Water	63.0 mg/mL (198.2 mM)
Ethanol	3.0 mg/mL (9.4 mM)

动物实验配方

靶点数据

生物活性

描述σ1 agonist (IC50 = 860 nM); also displays affinity for muscarinic M1-M4 receptors (Ki values < 500 nM), but not for σ2 receptors. Exhibits neuroprotective effects, prevents tau hyperphosphorylation, and attenuates scopolamine- and (+)-MK 801-induced learning deficits in a mouse model of amyloid toxicity.