CAS:1883727-34-1AMG-176

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AMG-176 Cat No. FB11323Cas No. 1883727-34-1

AMG-176 is an inhibitor of induced myeloid leukemia cell differentiation protein MCL-1 (myeloid cell leukemia-1), with potential pro-apoptotic and antineoplastic activities.

规格	价格	促销价格	库存

18817579266

立即询价

咨询

18817579266

立即询价

实验数据

储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 1.6308 mL
- 8.1538 mL
- 16.3076 mL
- 5 mM
- 0.3262 mL
- 1.6308 mL
- 3.2615 mL
- 10 mM
- 0.1631 mL
- 0.8154 mL
- 1.6308 mL
计算器摩尔计算器总药量计算器工作液计算器

技术信息

CAS号	1883727-34-1	储存条件	粉末 -20°C 3 年液体 -80°C 12 月
分子式	C33H41ClN2O5S	运输	蓝冰
分子量	613.21	别名

靶点数据

生物活性

描述AMG-176 is an inhibitor of induced myeloid leukemia cell differentiation protein MCL-1 (myeloid cell leukemia-1), with potential pro-apoptotic and antineoplastic activities. This disrupts the formation of MCL-1/Bcl-2-like protein 11 (BCL2L11; BIM) complexes and induces apoptosis in tumor cells. MCL-1, an anti-apoptotic protein belonging to the Bcl-2 family of proteins, is upregulated in cancer cells and promotes tumor cell survival.