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Synonyms: ACP-196
Acalabrutinib is a second-generation, selective and irreversible inhibitor of BTK (Bruton's tyrosine kinase) with an IC50 of 3 nM and EC50 of 8 nM in a human whole-blood CD69 B cell activation assay. Acalabrutinib has improved pharmacologic features, including favorable plasma exposure, rapid oral absorption, a short half-life, and the absence of irreversible targeting to alternative kinases.
规格 | 价格 | 促销价格 | 库存 |
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18817579266
实验数据
技术信息
CAS号 | 1420477-60-6 | 储存条件 |
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分子式 | C26H23N7O2 | 运输 | 蓝冰 | |||||||||||||
分子量 | 465.51 | 别名 | ACP-196 | |||||||||||||
溶解度 |
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动物实验配方 |
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靶点 | Description | IC50 |
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BTK | IC50:3nM |