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Synonyms: 5-Fluorouracil 1β-D-ribofuranoside;FUrd
5-Fluorouridine is a metabolite of 5-fluorouracil with anticancer activity and cytotoxic activity. 5-fluorouridine inhibits rRNA synthesis of human colon carcinoma cells. 5-Fluorouridine exhibits cytotoxic effect on growth of L1210 cells with an IC50 of 2 nM. 5-Fluorouridine triphosphate acted as a potent competitive inhibitor of VPg uridylylation, the initial step of viral replication.
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18817579266
实验数据
技术信息
CAS号 | 316-46-1 | 储存条件 |
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分子式 | C9H11FN2O6 | 运输 | 蓝冰 | |||||
分子量 | 262.19 | 别名 | 5-Fluorouracil 1β-D-ribofuranoside;FUrd | |||||
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生物活性