产品
编 号:F170246
分子式:C23H19ClN2O3
分子量:406.86
产品类型
结构图
CAS No: 146662-42-2
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产品详情
生物活性:
SR2640 (hydrochloride) is a potent and selective competitive leukotriene D4/leukotriene E4 antagonist. SR2640 can be used for researching the role of leukotrienes in human asthma.
体内研究:
SR2640 inhibits the LTD 4-induced contractions of guinea-pig ileum in a concentration-dependent manner, with an IC50 of 3 nM.SR2640 (1 mg/kg; IV; single dosage) specifically prevents the contractile responses of guinea-pig ileum and trachea to LTD4 and LTE4.Animal Model:Guinea pigs (injected with LTD4 and LTE4)
Dosage:1 mg/kg
Administration:IV; single dosage
Result:Specifically prevented the contractile responses of guinea-pig ileum and trachea to LTD4 and LTE4.