产品
编 号：F170116
分子式：C22H28Cl2F3N3OS
分子量：510.44
分子式：C22H28Cl2F3N3OS
分子量：510.44
产品类型
规格
价格
是否有货
100mg
询价
询价
结构图
CAS No: 146-56-5
产品详情
生物活性：
Fluphenazine dihydrochloride is a potent, orally active phenothiazine-based dopamine receptor antagonist. Fluphenazine dihydrochloride blocks neuronal voltage-gated sodium channels. Fluphenazine dihydrochloride acts primarily through antagonism of postsynaptic dopamine-2 receptors in mesolimbic, nigrostriatal, and tuberoinfundibular neural pathways. Fluphenazine dihydrochloride can antagonize Methylphenidate-induced stereotyped gnawing and inhibit climbing behaviour in mice. Fluphenazine dihydrochloride can be used for researching psychosis and painful peripheral neuropathy associated with diabetes and has potential to inhibit SARS-CoV-2.
体内研究：
Fluphenazine (1 mg/kg；IG，从妊娠第 6 天到第 15 天进行) dihydrochloride 会导致怀孕小鼠畸形。Fluphenazine (0.125-1 mg/kg；IP，单剂量) dihydrochloride 拮抗哌醋甲酯引起的刻板啃咬， 显着抑制攀爬行为。
Fluphenazine dihydrochloride is a potent, orally active phenothiazine-based dopamine receptor antagonist. Fluphenazine dihydrochloride blocks neuronal voltage-gated sodium channels. Fluphenazine dihydrochloride acts primarily through antagonism of postsynaptic dopamine-2 receptors in mesolimbic, nigrostriatal, and tuberoinfundibular neural pathways. Fluphenazine dihydrochloride can antagonize Methylphenidate-induced stereotyped gnawing and inhibit climbing behaviour in mice. Fluphenazine dihydrochloride can be used for researching psychosis and painful peripheral neuropathy associated with diabetes and has potential to inhibit SARS-CoV-2.
体内研究：
Fluphenazine (1 mg/kg；IG，从妊娠第 6 天到第 15 天进行) dihydrochloride 会导致怀孕小鼠畸形。Fluphenazine (0.125-1 mg/kg；IP，单剂量) dihydrochloride 拮抗哌醋甲酯引起的刻板啃咬， 显着抑制攀爬行为。
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