产品
编 号:F170042
分子式:C17H27Cl2N5
分子量:372.34
产品类型
结构图
CAS No: 146510-36-3
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产品详情
生物活性:
Olanexidine is an antibacterial agent. Olanexidine is active against a wide range of bacteria, imcluding both Gram-positive and Gram-negative bacteria Olanexidine is also an antiseptic. Olanexidine can be used in the research of infection and inflammation.
体内研究:
Olanexidine (1?-2% in saline, applied to the skin) is active against transient or resident bacterial flora on the skin of male cynomolgus monkeys.Animal Model:Male cynomolgus monkeys
Dosage:1?%, 1.5%, 2% in saline
Administration:Applied to the skin
Result:Showed the fast-acting and long-lasting bactericidal effects at 1.5% concentration.
体外研究:
Olanexidine (50 μM, 48 h) exhibits broad-spectrum bactericidal activity against Gram-positive cocci and Gram-negative bacteria.Olanexidine (50 μg/mL, 24 h) inhibits chronic inflammatory reactions in oral mucosal cells.Olanexidine (Olanexidine gluconate, 0-15000 μg/mL) inhibits the binding ability of virus-like particles to the binding receptor of human norovirus and increases the aggregation of virus-like particles.