产品
编 号：F169936
分子式：C8H12N4O
分子量：180.21
分子式：C8H12N4O
分子量：180.21
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CAS No: 146422-58-4
产品详情
生物活性：
CDD0102 is a potent M1 Muscarinic receptor agonist.
体内研究：
After i.p. injections, CDD0102 (CDD-0102) crosses the blood-brain barrier (BBB) in a dose-dependent manner. In toxicological studies, the LD50 of CDD0102 is 190 mg/kg following i.p. injections and greater than 1,000 mg/kg following oral administration. In follow-up studies, after oral administration at a dose of 10 mg/kg, CDD0102 fully reverses memory deficits associated with IgG-192 saporin administration. Again, no side effects are observed at this dose.
体外研究：
CDD0102 (CDD-0102) is an efficacious muscarinic agonist in cell lines expressing M1 receptors. CDD0102 displays much lower activity at M3 and M5 receptors.
CDD0102 is a potent M1 Muscarinic receptor agonist.
体内研究：
After i.p. injections, CDD0102 (CDD-0102) crosses the blood-brain barrier (BBB) in a dose-dependent manner. In toxicological studies, the LD50 of CDD0102 is 190 mg/kg following i.p. injections and greater than 1,000 mg/kg following oral administration. In follow-up studies, after oral administration at a dose of 10 mg/kg, CDD0102 fully reverses memory deficits associated with IgG-192 saporin administration. Again, no side effects are observed at this dose.
体外研究：
CDD0102 (CDD-0102) is an efficacious muscarinic agonist in cell lines expressing M1 receptors. CDD0102 displays much lower activity at M3 and M5 receptors.
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