产品
编 号：F168499
分子式：C61H88N18O16
分子量：1329.46
分子式：C61H88N18O16
分子量：1329.46
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
50mg
询价
询价
100mg
询价
询价
结构图
CAS No: 145781-92-6
产品详情
生物活性：
Goserelin acetate (ICI-118630 acetate), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions as a GnRH agonist. Goserelin acetate can be used for the research of breast cancer, epithelial ovarian cancer and prostate cancer.
体内研究：
Goserelin acetate (100 μg；皮下注射；每天；持续 19 天) 显著增加皮下异种移植肿瘤中凋亡细胞的比例。Animal Model:Five-week-old specific-pathogen free (SPF) female nude mice (18-20 g), subcutaneous xenograft tumor model
Dosage:100 μg/mice
Administration:Subcutaneous injection, daily, for 19 days
Result:Significantly increased the proportion of apoptotic cells in the subcutaneous xenograft tumors
体外研究：
Goserelin (1 nM-1 mM；48-72 hours) 促进EOC细胞凋亡。 Goserelin (100 μM；24-72 hours) 调节 SKOV3-ip 细胞中人凋亡相关基因的表达。 Goserelin (100 μM；24-72 hours) 通过 PI3K/AKT 信号通路上调 FOXO1 促进 EOC 细胞凋亡。
Goserelin acetate (ICI-118630 acetate), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions as a GnRH agonist. Goserelin acetate can be used for the research of breast cancer, epithelial ovarian cancer and prostate cancer.
体内研究：
Goserelin acetate (100 μg；皮下注射；每天；持续 19 天) 显著增加皮下异种移植肿瘤中凋亡细胞的比例。Animal Model:Five-week-old specific-pathogen free (SPF) female nude mice (18-20 g), subcutaneous xenograft tumor model
Dosage:100 μg/mice
Administration:Subcutaneous injection, daily, for 19 days
Result:Significantly increased the proportion of apoptotic cells in the subcutaneous xenograft tumors
体外研究：
Goserelin (1 nM-1 mM；48-72 hours) 促进EOC细胞凋亡。 Goserelin (100 μM；24-72 hours) 调节 SKOV3-ip 细胞中人凋亡相关基因的表达。 Goserelin (100 μM；24-72 hours) 通过 PI3K/AKT 信号通路上调 FOXO1 促进 EOC 细胞凋亡。
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备