产品
编 号：F167678
分子式：C6H6N2O
分子量：122.12
分子式：C6H6N2O
分子量：122.12
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
100mg
528
In-stock
250mg
1108
In-stock
500mg
1760
In-stock
结构图
CAS No: 1452-77-3
产品详情
生物活性：
Picolinamide (2-Picolinamide) is an inhibitor of Poly(ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.
体内研究：
Picolinamide (4 mmol/kg, i.p., rats) inhibits Na+/phosphate cotransport by isolated renal brush border membrane vesicles.Picolinamide (250 mg/kg, i.p., rats) enhances the tumorigenic effect of Streptozotocin and Alloxan on islet B-cells.Animal Model:Rats
Dosage:4 mmol/kg
Administration:Intraperitoneal injection (i.p.)
Result:Increased renal cortical NAD content (1.5 fold).
体外研究：
Picolinamide (10 μM-1 mM) inhibits Poly(ADP-ribose) synthetase activity.Picolinamide (2 mM) protects against streptozotocin-induced depression of proinsulin synthesis in isolated pancreatic islets of rats.
Picolinamide (2-Picolinamide) is an inhibitor of Poly(ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.
体内研究：
Picolinamide (4 mmol/kg, i.p., rats) inhibits Na+/phosphate cotransport by isolated renal brush border membrane vesicles.Picolinamide (250 mg/kg, i.p., rats) enhances the tumorigenic effect of Streptozotocin and Alloxan on islet B-cells.Animal Model:Rats
Dosage:4 mmol/kg
Administration:Intraperitoneal injection (i.p.)
Result:Increased renal cortical NAD content (1.5 fold).
体外研究：
Picolinamide (10 μM-1 mM) inhibits Poly(ADP-ribose) synthetase activity.Picolinamide (2 mM) protects against streptozotocin-induced depression of proinsulin synthesis in isolated pancreatic islets of rats.
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