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编 号：F167524
分子式：C171H283N55O49S8
分子量：4149.94
分子式：C171H283N55O49S8
分子量：4149.94
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CAS No: 145199-73-1
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生物活性：
Kaliotoxin is a peptidyl inhibitor of neuronal BK-Type. Kaliotoxin can specific inhibit Kv channels and calcium-activated potassium channels. Kaliotoxin can be used for the research of the regulation of membrane potential and neuron excitability.
体内研究：
Kaliotoxin facilitates cognitive processes by the blockage of Kv1.1 or Kv1.3 channels.Animal Model:Male Sprague–Dawley rats (280–300 g)
Dosage:10 ng
Administration:Intracerebroventricular injection
Result:Improved learning but not information consolidation.Increased the long-term retrieval of an odour-reward association.
体外研究：
Kaliotoxin (KTX) (250 nM) specifically suppressed the whole cell Ca2+-activated K+ current.Kaliotoxin interacts in a one-to-one way with KCa channels with a Kd of 20 nM.
Kaliotoxin is a peptidyl inhibitor of neuronal BK-Type. Kaliotoxin can specific inhibit Kv channels and calcium-activated potassium channels. Kaliotoxin can be used for the research of the regulation of membrane potential and neuron excitability.
体内研究：
Kaliotoxin facilitates cognitive processes by the blockage of Kv1.1 or Kv1.3 channels.Animal Model:Male Sprague–Dawley rats (280–300 g)
Dosage:10 ng
Administration:Intracerebroventricular injection
Result:Improved learning but not information consolidation.Increased the long-term retrieval of an odour-reward association.
体外研究：
Kaliotoxin (KTX) (250 nM) specifically suppressed the whole cell Ca2+-activated K+ current.Kaliotoxin interacts in a one-to-one way with KCa channels with a Kd of 20 nM.
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